ENSDARG00000054003


Danio rerio

Features
Gene ID: ENSDARG00000054003
  
Biological name :rargb
  
Synonyms : rargb / retinoic acid receptor, gamma b
  
Possible biological names infered from orthology : P13631 / P18911 / RARG / retinoic acid receptor gamma
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 2089461
Gene end: 2096469
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142165
swissprot - G1K2L7
ZFIN ID - ZDB-GENE-070314-1
Ensembl - ENSDARG00000054003
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RARGENSG00000172819Homo sapiens
 RargENSMUSG00000001288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rarga / Q91392 / retinoic acid receptor gamma a / RARG* / P18911* / P13631* / retinoic acid receptor gamma*ENSDARG0000003411791
rarab / Q7ZTI3 / retinoic acid receptor, alpha b / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000003489378
raraa / Q90271 / retinoic acid receptor, alpha a / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000005678377
thrab / thyroid hormone receptor alpha b / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000005265434
thraa / Q98867 / thyroid hormone receptor alpha a / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000000015133
thrb / Q9PVE4 / thyroid hormone receptor beta / P10828* / P37242*ENSDARG0000002116333
nr1h3 / nuclear receptor subfamily 1, group H, member 3 / Q13133*ENSDARG0000009843931
nr1h4 / nuclear receptor subfamily 1, group H, member 4 / Q60641* / Q96RI1* / Bile acid receptor *ENSDARG0000005774129
vdrb / Q1L673 / vitamin D receptor b / VDR* / P48281* / P11473* / vitamin D receptor* / vitamin D (1,25-dihydroxyvitamin D3) receptor*ENSDARG0000007072126
nr1i2 / nuclear receptor subfamily 1, group I, member 2 / O54915* / O75469*ENSDARG0000002976625
nr1h5 / nuclear receptor subfamily 1, group H, member 5ENSDARG0000003104623
vdra / vitamin D receptor a / VDR* / P11473* / vitamin D receptor*ENSDARG0000009948314
CABZ01088036.1 / VDR* / P11473* / vitamin D receptor*ENSDARG0000011292313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003078  Retinoic acid receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003708 retinoic acid receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver bilateral , abnormal
Show

 ZFA:0000436 spleen spleen decreased size , abnormal
spleen agenesis , abnormal
Show

 ZFA:0001719 presumptive cardiac ventricle heart tube presumptive cardiac ventricle heart tube mislocalised , abnormal
Show

 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct morphology , abnormal
intrahepatic bile duct decreased branchiness , abnormal
intrahepatic bile duct cell body increased size , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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