ENSDARG00000034893


Danio rerio

Features
Gene ID: ENSDARG00000034893
  
Biological name :rarab
  
Synonyms : Q7ZTI3 / rarab / retinoic acid receptor, alpha b
  
Possible biological names infered from orthology : P10276 / P11416 / RARA / retinoic acid receptor alpha
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 33065613
Gene end: 33259621
  
Corresponding Affymetrix probe sets: Dr.305.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000044676
Ensembl peptide - ENSDARP00000111644
NCBI entrez gene - 555364     See in Manteia.
swissprot - E7EZ95
swissprot - Q7ZTI3
ZFIN ID - ZDB-GENE-980526-72
Ensembl - ENSDARG00000034893
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RARAENSGALG00000037935Gallus gallus
 RARAENSG00000131759Homo sapiens
 RaraENSMUSG00000037992Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
raraa / Q90271 / retinoic acid receptor, alpha a / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000005678386
rarga / Q91392 / retinoic acid receptor gamma a / RARG* / P18911* / P13631* / retinoic acid receptor gamma*ENSDARG0000003411768
rargb / retinoic acid receptor, gamma b / RARG* / P13631* / retinoic acid receptor gamma*ENSDARG0000005400366
thraa / Q98867 / thyroid hormone receptor alpha a / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000000015129
thrab / thyroid hormone receptor alpha b / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000005265428
nr1h3 / nuclear receptor subfamily 1, group H, member 3 / Q13133*ENSDARG0000009843928
thrb / Q9PVE4 / thyroid hormone receptor beta / P10828* / P37242*ENSDARG0000002116328
nr1h4 / nuclear receptor subfamily 1, group H, member 4 / Q60641* / Q96RI1* / Bile acid receptor *ENSDARG0000005774124
nr1i2 / nuclear receptor subfamily 1, group I, member 2 / O54915* / O75469*ENSDARG0000002976623
vdrb / Q1L673 / vitamin D receptor b / VDR* / P48281* / P11473* / vitamin D receptor* / vitamin D (1,25-dihydroxyvitamin D3) receptor*ENSDARG0000007072123
nr1h5 / nuclear receptor subfamily 1, group H, member 5ENSDARG0000003104620
vdra / vitamin D receptor a / VDR* / P11473* / vitamin D receptor*ENSDARG0000009948312
CABZ01088036.1 / VDR* / P11473* / vitamin D receptor*ENSDARG0000011292310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003078  Retinoic acid receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0030917 midbrain-hindbrain boundary development IGI
 biological_processGO:0033339 pectoral fin development IDA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003708 retinoic acid receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver absent , abnormal
liver decreased size , abnormal
Show

 ZFA:0000141 pectoral fin bud pectoral fin bud aplastic , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin absent , abnormal
pectoral fin aplastic , abnormal
Show

 ZFA:0005317 pectoral fin fold pectoral fin fold scapulocoracoid absent , abnormal
pectoral fin fold endochondral bone absent , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000030449 crabp2b / cellular retinoic acid binding protein 2, b / CRABP2* / P22935* / P29373* / cellular retinoic acid binding protein 2*  / reaction / complex
 ENSDARG00000057737 rxraa / retinoid X receptor, alpha a / RXRA* / P19793* / P28700* / retinoid X receptor alpha*  / complex
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000073978 crabp2a / cellular retinoic acid binding protein 2, a / CRABP2* / P22935* / P29373* / cellular retinoic acid binding protein 2*  / reaction / complex
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / reaction






 

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