ENSDARG00000052654


Danio rerio

Features
Gene ID: ENSDARG00000052654
  
Biological name :thrab
  
Synonyms : thrab / thyroid hormone receptor alpha b
  
Possible biological names infered from orthology : P10827 / P63058 / THRA / thyroid hormone receptor, alpha
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 21799130
Gene end: 22039350
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127358
Ensembl peptide - ENSDARP00000143264
NCBI entrez gene - 558427     See in Manteia.
swissprot - A0A286Y807
swissprot - U3JAT9
ZFIN ID - ZDB-GENE-060613-1
Ensembl - ENSDARG00000052654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 THRAENSGALG00000040017Gallus gallus
 THRAENSG00000126351Homo sapiens
 ThraENSMUSG00000058756Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
thraa / Q98867 / thyroid hormone receptor alpha a / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000000015191
thrb / Q9PVE4 / thyroid hormone receptor beta / P10828* / P37242*ENSDARG0000002116377
rargb / retinoic acid receptor, gamma b / RARG* / P13631* / retinoic acid receptor gamma*ENSDARG0000005400333
rarga / Q91392 / retinoic acid receptor gamma a / RARG* / P18911* / P13631* / retinoic acid receptor gamma*ENSDARG0000003411732
rarab / Q7ZTI3 / retinoic acid receptor, alpha b / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000003489332
raraa / Q90271 / retinoic acid receptor, alpha a / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000005678332
nr1h3 / nuclear receptor subfamily 1, group H, member 3 / Q13133*ENSDARG0000009843928
vdrb / Q1L673 / vitamin D receptor b / VDR* / P48281* / P11473* / vitamin D receptor* / vitamin D (1,25-dihydroxyvitamin D3) receptor*ENSDARG0000007072128
nr1h4 / nuclear receptor subfamily 1, group H, member 4 / Q60641* / Q96RI1* / Bile acid receptor *ENSDARG0000005774128
nr1i2 / nuclear receptor subfamily 1, group I, member 2 / O54915* / O75469*ENSDARG0000002976626
nr1h5 / nuclear receptor subfamily 1, group H, member 5ENSDARG0000003104622
CABZ01088036.1 / VDR* / P11473* / vitamin D receptor*ENSDARG0000011292314
vdra / vitamin D receptor a / VDR* / P11473* / vitamin D receptor*ENSDARG0000009948313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR001728  Thyroid hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004887 thyroid hormone receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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