ENSMUSG00000037992


Mus musculus

Features
Gene ID: ENSMUSG00000037992
  
Biological name :Rara
  
Synonyms : P11416 / Rara / retinoic acid receptor, alpha
  
Possible biological names infered from orthology : P10276
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 98927818
Gene end: 98974942
  
Corresponding Affymetrix probe sets: 10381082 (MoGene1.0st)   1450180_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103099
Ensembl peptide - ENSMUSP00000103097
Ensembl peptide - ENSMUSP00000103098
Ensembl peptide - ENSMUSP00000069744
Ensembl peptide - ENSMUSP00000129791
NCBI entrez gene - 19401     See in Manteia.
MGI - MGI:97856
RefSeq - XM_017314353
RefSeq - NM_001176528
RefSeq - NM_001177302
RefSeq - NM_001177303
RefSeq - NM_009024
RefSeq - XM_006532592
RefSeq - XM_006532593
RefSeq - XM_006532596
RefSeq - XM_006532597
RefSeq Peptide - NP_001169999
RefSeq Peptide - NP_001170773
RefSeq Peptide - NP_001170774
RefSeq Peptide - NP_033050
swissprot - Q3U3R3
swissprot - P11416
Ensembl - ENSMUSG00000037992
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 raraaENSDARG00000056783Danio rerio
 rarabENSDARG00000034893Danio rerio
 RARAENSGALG00000037935Gallus gallus
 RARAENSG00000131759Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rarb / P22605 / retinoic acid receptor, beta / P10826*ENSMUSG0000001749172
Rarg / P18911 / Retinoic acid receptor gamma / P13631*ENSMUSG0000000128868
Thrb / P37242 / Thyroid hormone receptor beta / P10828*ENSMUSG0000002177928
Thra / P63058 / Thyroid hormone receptor alpha / P10827*ENSMUSG0000005875628
Nr1h3 / Q9Z0Y9 / Mus musculus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 3, mRNA. / Q13133* / nuclear receptor subfamily 1 group H member 3*ENSMUSG0000000210827
Nr1h2 / Q60644 / Oxysterols receptor LXR-beta / P55055* / nuclear receptor subfamily 1 group H member 2*ENSMUSG0000006060127
Nr1i2 / O54915 / Nuclear receptor subfamily 1 group I member 2 / O75469*ENSMUSG0000002280926
Nr1h4 / Q60641 / Bile acid receptor / Q96RI1* / nuclear receptor subfamily 1 group H member 4*ENSMUSG0000004763824
Nr1h5ENSMUSG0000004893823
Vdr / P48281 / vitamin D (1,25-dihydroxyvitamin D3) receptor / P11473* / vitamin D receptor*ENSMUSG0000002247923
Nr1i3 / O35627 / Nuclear receptor subfamily 1 group I member 3 / Q14994*ENSMUSG0000000567721


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003078  Retinoic acid receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0001657 ureteric bud development IMP
 biological_processGO:0001843 neural tube closure IGI
 biological_processGO:0001889 liver development IEA
 biological_processGO:0002068 glandular epithelial cell development IGI
 biological_processGO:0003148 outflow tract septum morphogenesis IGI
 biological_processGO:0003417 growth plate cartilage development IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IGI
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0030852 regulation of granulocyte differentiation IMP
 biological_processGO:0030853 negative regulation of granulocyte differentiation IEA
 biological_processGO:0031076 embryonic camera-type eye development IGI
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032736 positive regulation of interleukin-13 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0032754 positive regulation of interleukin-5 production IEA
 biological_processGO:0033189 response to vitamin A IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0035264 multicellular organism growth IGI
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045596 negative regulation of cell differentiation IMP
 biological_processGO:0045630 positive regulation of T-helper 2 cell differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045947 negative regulation of translational initiation IDA
 biological_processGO:0048167 regulation of synaptic plasticity IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway ISO
 biological_processGO:0051099 positive regulation of binding IEA
 biological_processGO:0055012 ventricular cardiac muscle cell differentiation IMP
 biological_processGO:0060010 Sertoli cell fate commitment IMP
 biological_processGO:0060173 limb development IGI
 biological_processGO:0060324 face development IGI
 biological_processGO:0060348 bone development IGI
 biological_processGO:0060534 trachea cartilage development IMP
 biological_processGO:0060591 chondroblast differentiation IMP
 biological_processGO:0061037 negative regulation of cartilage development IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071391 cellular response to estrogen stimulus IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001012 RNA polymerase II regulatory region DNA binding IDA
 molecular_functionGO:0001972 retinoic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003708 retinoic acid receptor activity ISO
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043422 protein kinase B binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IGI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IMP
 molecular_functionGO:0044323 retinoic acid-responsive element binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0048027 mRNA 5"-UTR binding IEA
 molecular_functionGO:0051018 protein kinase A binding IEA
 molecular_functionGO:0051393 alpha-actinin binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000079 abnormal basioccipital bone morphology "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000159 abnormal xiphoid process "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000163 abnormal cartilage morphology "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Raratm1Ipc/Rara+,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
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Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0000468 abnormal esophageal epithelium morphology "malformation of the epithelial layer of the esophagus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0000471 abnormal stomach epithelium morphology "malformation of the epithelial layer of the stomach " [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0000484 abnormal pulmonary artery morphology "structrual anomaly of the artery that arises from the right ventricle and conveys unaerated blood to the lungs " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, hdene:Howard Dene, Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000520 absent kidney "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0000534 abnormal ureter morphology "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000536 hydroureter "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0000571 interdigital webbing "fold of skin, or web, between the toes that is not normally present" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0000703 abnormal thymus morphology "anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001076 abnormal hypoglossal nerve morphology "malformation or misprojection of motor axons to the tongue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0001120 abnormal uterus morphology "malformation or absence of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Raratm3.1Ipc/Raratm3.1Ipc
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0001178 pulmonary hypoplasia "reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Raratm3.1Ipc/Raratm3.1Ipc
Genetic Background: involves: 129/Sv * C57BL/6 * SJL

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tlr3tm1Flv/Tlr3tm1Flv
Genetic Background: involves: C57BL/6

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: H2-DMatm1Luc/H2-DMatm1Luc,Cd74tm1Doi/Cd74tm1Doi
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0002127 abnormal cardiovascular system morphology "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa3tm1Mrc/Hoxa3tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0002132 abnormal respiratory system morphology "anomalous structure of pulmonary tissues " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Rev/Raratm1Rev
Genetic Background: involves: 129S4/SvJae

 MP:0002257 abnormal arytenoid cartilage morphology "any structural anomaly of the paired triangular cartilages located postlaterally at the level of the thyroid cartilage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002258 abnormal cricoid cartilage morphology "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Rara+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002260 abnormal thyroid cartilage morphology "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002265 abnormal left major bronchus morphology "any structural anomaly of the conducting airway leading to the left lobe of the lungs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0002266 abnormal right major bronchus morphology "any structual anomaly of the conducting airway leading to the right lobe of the lungs " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0002401 abnormal lymphopoiesis "atypcial formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Otx1tm1Sia/Otx1tm1Sia,Otx2tm10Sia/Otx2tm10Sia
Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

 MP:0002633 persistent truncus arteriosis "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0002747 abnormal aortic valve morphology "malformation of the valve between the left ventricle and the ascending aorta" [J:82728, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0003007 ectopic thymus "ectopic location of the thymus primordium, which normally resides in the superior mediastinum and lower part of the neck" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:76015]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003036 vertebral transformation "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003049 abnormal lumbar vertebrae morphology "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003056 abnormal hyoid bone "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

 MP:0003120 abnormal tracheal cartilage "any structural anomaly of the cartilaginous structures that support the trachea" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:97123]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003235 abnormal alisphenoid bone morphology "malformation in either of the broad curved winglike expanses on each side of the sphenoid bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93183, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003321 tracheoesophageal fistula "an abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003446 renal hypoplasia "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003557 absent vas deferens "absence of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003558 absent uterus "absence of the female muscular organ of gestation" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003575 absent oviduct "absence of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003600 ectopic kidney 
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003642 absent seminal gland "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003722 absent ureter "missing the tube that conducts the urine from the renal pelvis to the bladder" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003869 ectopic cartilage "positional abnormality of cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0003893 increased hepatocyte proliferation "anomalous growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Mmp14tm1Hbh/Mmp14+,Mmp16tm1Khol/Mmp16+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Raratm3Ipc/Raratm3Ipc,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0003924 herniated diaphragm "protrusion of abdominal contents into the thoracic cavity through the diaphragm" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004158 right aortic arch "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004423 abnormal squamosal bone morphology "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004550 short trachea "reduced length of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0004553 absent tracheal cartilage rings "absence of the 16-20 incomplete rings of hyaline cartilage forming the skeleton of the trachea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004613 fusion of vertebral arches "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004615 cervical vertebral transformation "homeotic transformation of any cervical vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Rara+,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004616 lumbar vertebral transformation "homeotic transformation of any lumbar vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004620 cervical vertebral fusion "the union of one or more cervical vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0004666 absent stapedial artery "absence of the small artery that passes through the ring of the stapes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004936 abnormal ureteric bud branching morphogenesis "partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0005106 abnormal incus morphology "structural anomaly of the middle of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005107 abnormal stapes morphology "structural anomaly of the smallest and innermost of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005287 narrow eye opening "less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Rara+,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006063 abnormal inferior vena cava morphology "structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006354 abnormal fourth branchial arch artery morphology "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0006355 abnormal sixth branchial arch artery morphology "any structural anomaly of the vessels formed within the sixth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006425 absent Mullerian ducts "absence of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [J:40605, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008380 abnormal gonial bone morphology "any structural abnormality of the investing bone that lies on the surface of the malleus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008823 abnormal ventricular membranous septum morphology "any structural anomaly of the membranous portion of the wall between the two lower chambers of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0008881 absent Harderian gland "absence of the sebaceous gland located behind the eyeball in the orbit that excretes fluid that facilitates movement of the third eyelid" [MESH:A13.445]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0009054 absent anal canal "absence of the terminal portion of the alimentary canal" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009072 absent cranial vagina "absence of the upper third of the female reproductive canal located between the uterus and the vulva, usually due to a developmental arrest or agenesis of the caudal Mullerian ducts" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009075 rudimentary Wolffian ducts "not fully developed or remnants of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and later develop into the ductus deferens in the male" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0009076 rudimentary Mullerian ducts "not fully developed or remnants of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and in the female develop into the oviducts, uterus, and cranial vagina" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0009438 fusion of cricoid and tracheal cartilages "union of the cricoid cartilage and one or more of the tracheal rings into one structure, when this fusion does not normally occur" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0009569 abnormal left lung morphology "any structural anomaly of the organ of respiration located on the left side of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0009570 abnormal right lung morphology "any structural anomaly of the organ of respiration located on the right side of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0009571 abnormal right lung accessory lobe morphology 
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010418 perimembraneous ventricular septal defect "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010502 ventricle myocardium hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the ventricular part of the heart myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010565 absent fetal ductus arteriosus "absence of the fetal vessel that connects the left pulmonary artery with the descending aorta" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

 MP:0010572 persistent right dorsal aorta "persistence of the right dorsal aorta after development; the right dorsal aorta normally regresses but when it persists, a double aortic arch develops; if the left dorsal aorta also regresses, a right aortic arch forms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010584 abnormal conotruncus septation "anomaly in the process in which the conotruncus separates into the conus cordis, which will give rise to the outflow regions of the ventricles, and the truncus arteriosus which will be divided into proximal ends of the ascending aorta and pulmonary trunk" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010595 abnormal aortic valve cusp morphology "any structural anomaly of the three fibrous triangular components and associated flap of the aortic valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0010701 fusion of atlas and odontoid process "the large protuberance that projects upward from the cervical axis (C2), around which the cervical atlas normally rotates, is instead fused to elements of the atlas; the odontoid process may or may not remain attached to the axis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Rara+,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010702 split cervical atlas 
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010703 split cervical axis 
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarb+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Rara+,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010711 persistent hyperplastic primary vitreous "persistence of the embryonic fibrovascular mesodermal tissue located between the optic cup and lens vesicle that normally regresses during the development of the vitreous body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010721 short sublingual duct "decreased length of the canals that drain the sublingual gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010722 persistent cervical thymus "the solid lobe of the thymus fails to descend to the mediastinum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010728 fusion of atlas and occipital bones "union of elements of the atlas and the bone at the lower, posterior part of the skull into one structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010978 absent ureteric bud "absence of the epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme" [PMID:19828308]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010980 ectopic ureteric bud "ureteric bud(s) are not located in the normal or expected position" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0010983 abnormal ureteric bud invasion "any anomaly in the process in which the ureteric bud grows into the metanephric mesenchyme, and contributes to the formation of the metanephros" [PMID:19828308]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010984 abnormal metanephric mesenchyme morphology "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0010987 abnormal nephrogenic mesenchyme morphogenesis "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing nephron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0010989 fused bronchial cartilage rings "fusion of the hyaline cartilaginous structures that support the bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011290 decreased nephron number "reduction in the total number of filtering units of the kidney" [MGI:anna]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

 MP:0011294 renal glomerulus hypertrophy "increase in the bulk size of the capillary loops of the kidney that normally function as a filtration unit, due to cell enlargement" [MGI:anna]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011306 absent kidney pelvis "absence of the funnel shaped proximal portion of the ureter, normally formed by convergence of the major calices" [MGI:anna]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011407 absent nephrogenic zone "absence of the region found at the periphery of the developing metanephros within which the metanephric mesenchyme aggregates around the tips of the ureteric tree to form the nephrons;in rodents including mice, this region normally persists for a few days postnatally, although it is lost in humans by 36 weeks of gestation" [PMID:17452023]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Ipc/Rarb+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0011486 ectopic ureter "an abnormally placed opening of the ureter, either into the urinary bladder or at another site in the lower urinary or genital tract" [MGI:anna]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0013233 ectopic thyroid gland "a thyroid gland located outside of its normal position anterior to the laryngeal cartilages; usually due to abnormal migration of the thyroid diverticulum down from the foramen cecum at the posterior aspect of the tongue to its permanent pre-tracheal location; ectopic thyroid tissue is frequently found along the course of the thyroglossal duct or laterally in the neck, as well as in distant places such as the mediastinum and the subdiaphragmatic organs; the most common ectopic location is near its embryological origin at the foramen caecum, resulting in a lingual thyroid" [MGI:anna]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0013574 ectopic parathyroid gland "a parathyroid gland located outside of its normal position; in the normal adult mouse, the parathyroids are usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; because of their common pharyngeal pouch origin, ectopic thyroid and parathyroid tissue can occasionally be found in the thymus" [MGI:Anna]
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Allelic Composition: Myo7ash1-6J/Myo7ash1-6J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Rarbtm1Ipc/Rarbtm1Ipc
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Raratm2Ipc/Raratm2Ipc,Raratm1Ipc/Rara+,Rargtm1Ipc/Rargtm1Ipc
Genetic Background: involves: 129S2/SvPas

 MP:0013826 absent hypoglossal canal "absence of the bony canal in the occipital bone through which the hypoglossal nerve emerges from the skull" [ISBN:0683400088]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0030406 absent stapes obturator foramen "missing the central foramen (hole) located between the crura and the footplate of the stapes through which the stapedial artery passes" [MGI:anna]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rarbtm1Mma/Rarbtm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0030416 absent temporal bone zygomatic process "missing the long, arched process that projects from the lower region of the squamous part of the temporal bone and articulates with the zygomatic bone" [MGI:anna]
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Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm4Ipc/Rargtm4Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas

Allelic Composition: Raratm1Ipc/Raratm1Ipc,Rargtm2Ipc/Rargtm2Ipc
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000004885 Crabp2 / P22935 / Cellular retinoic acid-binding protein 2 / P29373*  / complex / reaction
 ENSMUSG00000015846 Rxra / P28700 / retinoid X receptor alpha / P19793*  / complex






 

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contact: otassy@igbmc.fr