| MP:0000062 | increased bone density | "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Pvalbtm5.1(cre/folA)Hze/Pvalb+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Allelic Composition: Vdrtm1.1Pcn/Vdr+
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Vdrtm1Mbd/Vdr+
Genetic Background: involves: 129S4/SvJae
|
| MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
| MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000135 | reduced cortical bone thickness | "thinner than normal superficial layer of compact bone " [J:61509] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000165 | abnormal hypertrophic chondrocyte zone | "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000166 | abnormal chondrocyte morphology | "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Ggta1tm1Jbl/Ggta1+,Ightm1Jiac/Ightm1Jiac,Igktm1Jiac/Igktm1Jiac
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
|
| MP:0000195 | hypocalcemia | "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
|
| MP:0000198 | hypophosphatemia | "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0000219 | increased neutrophil count | "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000231 | hypertension | "sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
|
| MP:0000367 | abnormal coat/ hair morphology | "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
|
| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000488 | abnormal intestinal epithelium morphology | "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0000493 | rectal prolapse | "downward movement and external appearance of the rectum through the anus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0000511 | abnormal intestinal mucosa morphology | "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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| MP:0000512 | intestinal ulcer | "lesions in the mucous lining of the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
|
| MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0000691 | enlarged spleen | "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0000708 | thymus hyperplasia | "increased cell number in the thymus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001121 | uterine hypoplasia | "reduced size of the uterus due to decreased cell number" [J:45065] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001132 | absent mature ovarian follicles | "failure of ovarian follicle differentiation" [J:35782] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001145 | abnormal male reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001194 | dermatitis | "inflammation of the skin" [J:65146] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001239 | abnormal granular layer morphology | "structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001246 | mixed cellular infiltration to dermis | "gradual accumulation of mixed cell types in the dermis that are not normally found there" [J:65416] |
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Allelic Composition: Htr2atm1Grch/Htr2atm2Grch,Slc6a4tm1(cre)Grch/Slc6a4+
Genetic Background: involves: 129S6/SvEvTac
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| MP:0001247 | dermal cysts | "abnormal membranous sacs appearing in the dermis" [J:53379] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
|
| MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001283 | sparse vibrissae | "few and widely spaced whiskers" [J:65302] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001407 | short stride length | "reduced average distance between steps" [J:34193] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001413 | abnormal response to new environment | "altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001486 | abnormal startle reflex | "abberant threshold or reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3] |
Show
Allelic Composition: Pcdh15av-6J/Pcdh15av-6J
Genetic Background: B6(129P2)-Pcdh15av-6J
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| MP:0001533 | abnormal skeleton physiology | "anomalous function of the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pdgfrbredeye/Pdgfrbredeye
Genetic Background: C3N.C-Pdgfrbredeye
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| MP:0001566 | hyperphosphatemia | "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
Show
Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
|
| MP:0001750 | increased circulating follicle stimulating hormone level | "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0001762 | polyuria | "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
Show
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
|
| MP:0001824 | abnormal thymic involution | "premature or late decline in thymic function normally associated with advancing age" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0001849 | ear inflammation | "local accumulation of fluid, plasma proteins and leukocytes in the ear" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Htr2atm1Grch/Htr2atm2Grch,Slc6a4tm1(cre)Grch/Slc6a4+
Genetic Background: involves: 129S6/SvEvTac
|
| MP:0001858 | intestinal inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Runx1tm2Buch/Runx1tm2Buch,Tg(Mx1-cre)1Cgn/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0001927 | abnormal oestrous cycle (sensu Rodentia) | "failure of or aberrant timing of the sexual cycle of female animals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0001929 | abnormal gametogenesis | "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0002161 | abnormal fertility/fecundity | "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0002451 | abnormal macrophage physiology | "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
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| MP:0002675 | asthenozoospermia | "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
|
| MP:0002757 | reduced vertical activity | "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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| MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
|
| MP:0002816 | colitis | "local accumulation of fluid, plasma proteins, and leukocytes in the colon region of the large intestine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0002833 | increased heart weight | "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Vdrtm1Mbd/Vdr+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0002904 | increased circulating parathyroid hormone level | "greater than expected blood concentration of this regulator of calcium and phosphorous concentration" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002953 | thick ventricular wall | "increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
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| MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
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| MP:0003112 | enlarged parathyroid gland | |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
|
| MP:0003116 | rickets | "overproduction and deficient calcification of osteoid tissue due to vitamin D deficiency; can lead to skeletal deformities, growth defects, hypocalcemia, and sometimes tetany; skeletal fractures occur frequently" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003141 | cardiac fibrosis | "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003313 | abnormal locomotor activation | "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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| MP:0003352 | increased circulating renin level | "elevated blood concentration of this enzyme which is secreted by the kidney; it cleaves a bond in angiotensionogen to generate angiotensin I " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6J
|
| MP:0003414 | epidermal cyst | "a cyst formed of a mass of epidermal cells which is present beneath the epidermis; the wall is lined with stratified squamous epithelium and exhibits increased/abnormal keratinization" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf23tm1Blan/Fgf23tm1Blan,Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
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| MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0003432 | increased activity of parathyroid | "increased function of this paired endocrine gland that normally produces parathyroid hormone (PTH) that regulates calcium and phosphorous metabolism" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003493 | parathyroid hyperplasia | |
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Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003639 | abnormal response to vitamins | "altered ability or inability to respond to or metabolize a group of organic substances that are required in trace amounts for the normal metabolic homeostasis of the body " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0003795 | abnormal bone structure | |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0003915 | increased left ventricle weight | "greater than average weight of the left ventricle compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0003941 | abnormal skin development | "anomaly in the formation of of the membranous protective covering of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0003957 | abnormal nitric oxide homeostasis | "anomaly in the state of equilibrium in the body of nitric oxide, a free radical gas and a potent vasodilator" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
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| MP:0004215 | abnormal myocardial fiber physiology | "anomaly in the function of the multinucleated muscle cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0004564 | enlarged myocardial fiber | "increased size of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0004803 | increased susceptibility to autoimmune diabetes | "greater likelihood that an organism will develop inflammatory pancreatic disease resulting from the body attacking and destroying the insulin-producing beta islet cells of the pancreas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0004804 | decreased susceptibility to autoimmune diabetes | "reduced likelihood that an organism will develop inflammatory pancreatic disease resulting from the body attacking and destroying the insulin-producing beta islet cells of the pancreas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0004842 | abnormal large intestine crypts of Lieberkuhn morphology | "any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the large intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0004851 | increased testis weight | "greater average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0004876 | decreased mean arterial blood pressure | "decrease in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0004905 | decreased uterus weight | "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004955 | increased thymus weight | "greater than average weight of the primary lymphoid organ that is required for maturation of T cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0004974 | decreased regulatory T cell number | "reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0004985 | decreased osteoclast cell number | "reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Tg(Col1a1-cre)1Kry/0,Vdrtm1Pcn/Vdrtm1Pcn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
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| MP:0004988 | increased osteoblast cell number | "greater than average number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0004993 | decreased bone resorption | "reduced amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(Col1a1-cre)1Kry/0,Vdrtm1Pcn/Vdrtm1Pcn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
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| MP:0005016 | decreased lymphocyte number | "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0005026 | decreased susceptibility to parasitic infection | "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: B6.129-Vdrtm1Rge
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| MP:0005046 | failure of spleen white pulp formation | "lack of development of the lymphoid area of the spleen" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0005095 | decreased T cell proliferation | "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0005291 | abnormal glucose tolerance | "deviation from the normal response to oral consumption or intravenous injection of specified amounts of glucose; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0005294 | abnormal heart ventricle morphology | "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0005401 | abnormal fat-soluble vitamin level | "anomalous concentration of any of the organic substances found in food that are necessary in trace amounts for normal metabolic function and which require the presence of lipids for assimilation in the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0005425 | increased macrophage count | "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0005441 | hypercalciuria | "excretion of abnormally large amounts of calcium in the urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86949] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0005463 | abnormal CD4+ T cell physiology | "anomalous response of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0005522 | increased circulating atrial natriuretic factor | "greater than the normal concentration of this peptide hormone in the blood; it regulates the water-electrolyte balance and acts as a vasodilator" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Vdrtm1.2Sgcg/Vdrtm1.2Sgcg
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0005581 | abnormal renin activity | "alterated ability of this enzyme to cleave angiotensinogen and create angiotensin I" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0005582 | increased renin activity | "greater than the normal ability of this enzyme to cleave angiotensinogen and create angiotensin I" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0005602 | decreased angiogenesis | "reduced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission] |
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Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0005605 | increased bone mass | "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pvalbtm5.1(cre/folA)Hze/Pvalb+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Allelic Composition: Vdrtm1.1Pcn/Vdr+
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Vdrtm1Mbd/Vdr+
Genetic Background: involves: 129S4/SvJae
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| MP:0005619 | increased potassium excretion | "greater than the normal amount of this alkaline metallic element, the most abundant intracellular ion, voided by the kidneys" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0005636 | abnormal mineral homeostasis | "anomaly in the state of equilibrium in the body with respect to any of the inorganic substance that have importance in body functions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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| MP:0006143 | increased diastolic blood pressure | "abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0006144 | increased systolic blood pressure | "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0006263 | decreased diastolic blood pressure | "abnormal decrease in the pressure in the arteries between heart beats when the heart is relaxed" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:21887] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0006264 | decreased systolic blood pressure | "abnormal decrease in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:21887] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0006316 | increased urine sodium level | "higher than normal concentration of sodium in the urine" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0006375 | increased circulating angiotensinogen level | "greater than normal concentration of the serum globulin formed by the liver that is cleaved by renin to form angiotensin I" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0006387 | abnormal T cell number | "deviation from the normal count of T cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
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Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0006397 | disorganized long bone epiphyseal plate | "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0006398 | increased long bone epiphyseal plate size | "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0006413 | increased T cell apoptosis | "increase in the number of T cells undergoing programmed cell death" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0008115 | abnormal dendritic cell differentiation | "atypical production of or inability to produce a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0008396 | abnormal osteoclast differentiation | "atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(Col1a1-cre)1Kry/0,Vdrtm1Pcn/Vdrtm1Pcn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
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| MP:0008466 | enlarged mesenteric lymph nodes | "increased size of the lymph nodes located in the mesentary, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0008476 | increased spleen red pulp amount | "increase in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0008537 | increased susceptibility to induced colitis | "increased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0008650 | abnormal interleukin-1 secretion | "anomaly in the production or release of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens" [MESH:D12.644.276.374.465.501] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0008706 | decreased interleukin-6 secretion | "reduction in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0008713 | abnormal cytokine level | "deviation from the normal levels of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0008722 | abnormal chemokine secretion | "anomaly in the production or cellular release of any of the class of pro-inflammatory cytokines that attract and activate leukocytes" [MESH:D12.644.276.374.200] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: NOD.Cg-Vdrtm1Ska/CmatJ
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| MP:0008751 | abnormal interleukin level | "deviation from the normal levels of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0008752 | abnormal tumor necrosis factor level | "deviation from the normal levels of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [MESH:D12.644.276.374.500.800] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0008826 | abnormal splenic cell ratio | "deviation from the standard ratios of splenocyte subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0008828 | abnormal lymph node cell ratio | "deviation from the standard ratios of lymph node cell subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0009142 | decreased prepulse inhibition | "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Ska/Vdrtm1Ska
Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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| MP:0009257 | dilated seminiferous tubules | "the luminal space of the seminiferous tubules is increased in volume or area, usually with an increase in contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0009335 | decreased splenocyte proliferation | "reduction in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0009543 | abnormal thymus corticomedullary boundary morphology | "any structural anomaly of the dense region demarcating the thymus medulla from the surrounding cortex that is characterized by numerous
blood vessels (predominantly arterioles) with some perivascular connective tissue, mature and immature T lymphocytes, dendritic cells, variable numbers of perivascular B-lymphocytes and plasma cells; site of entry of bone marrow stem cells and exit of mature,
functional T cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17067941] |
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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| MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0009643 | abnormal urine homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009766 | increased sensitivity to xenobiotic induced morbidity/mortality | "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0010724 | thick interventricular septum | "increased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Vdrtm1.1Sgcg/Vdrtm1.2Sgcg,Myl2tm1(cre)Krc/Myl2+
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL
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| MP:0010760 | abnormal macrophage chemotaxis | "anomaly in the movement of a macrophage guided by a specific chemical concentration gradient" [GO:0048246] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0010878 | increased trabecular bone volume | "increase in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tg(Col1a1-cre)1Kry/0,Vdrtm1Pcn/Vdrtm1Pcn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Allelic Composition: Vdrtm1.1Pcn/Vdr+
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Allelic Composition: Vdrtm1Mbd/Vdr+
Genetic Background: involves: 129S4/SvJae
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| MP:0010926 | increased osteoid volume | "increase in the amount of space occupied by newly formed organic bone matrix secreted by osteoblasts" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0011221 | decreased intestinal calcium absorption | "reduced ability of the body to take up calcium into the blood by absorption from the small intestine" [MGI:csmith] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
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| MP:0011228 | abnormal vitamin D level | "any anomaly in the concentration of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism; specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)" [GO:0042368] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1Tyam/Vdrtm1Tyam
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Vdrtm1.1Gcm/Vdrtm1.1Gcm
Genetic Background: involves: 129 * BALB/c * C57BL/6 * Swiss
Allelic Composition: Tg(Col2a1-cre)1Bhr/?,Vdrtm1Gcm/Vdrtm1Gcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Vdrtm1Rge/Vdrtm1Rge
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Vdrtm1.1Pcn/Vdrtm1.1Pcn
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
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| MP:0011941 | increased fluid intake | "increase in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae
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| MP:0012175 | flat face | "the appearance of a flattened surface outline or contour of a normally rounded face of an organism" [MGI:anna] |
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Allelic Composition: Uncxtm1Pgr/Uncxtm1Pgr
Genetic Background: involves: NMRI
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| MP:0020010 | decreased bone mineral density of femur | "reduction in the amount of mineral per square centimeter of bone (usually g/cm2) in the long bone of the thigh" [GOC:NV] |
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Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6
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