ENSDARG00000056653


Danio rerio

Features
Gene ID: ENSDARG00000056653
  
Biological name :fhl1b
  
Synonyms : fhl1b / four and a half LIM domains 1b
  
Possible biological names infered from orthology : FHL1 / Fhl4 / four and a half LIM domains 1 / Four and a half LIM domains protein 1 / P97447 / Q13642
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 26597990
Gene end: 26621189
  
Corresponding Affymetrix probe sets: Dr.16511.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073643
Ensembl peptide - ENSDARP00000115361
NCBI entrez gene - 387528     See in Manteia.
RefSeq - XM_009305310
swissprot - F1Q7A2
ZFIN ID - ZDB-GENE-031219-1
Ensembl - ENSDARG00000056653
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FHL1ENSGALG00000006190Gallus gallus
 FHL1ENSG00000022267Homo sapiens
 Fhl1ENSMUSG00000023092Mus musculus
 Fhl4ENSMUSG00000050035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fhl1a / four and a half LIM domains 1a / FHL1* / Fhl4* / Q13642* / P97447* / four and a half LIM domains 1* / Four and a half LIM domains protein 1 *ENSDARG0000007149867
fhl2b / four and a half LIM domains 2b / FHL2* / O70433* / Q14192* / four and a half LIM domains 2* / Four and a half LIM domains protein 2 *ENSDARG0000000399148
fhl2a / four and a half LIM domains 2a / FHL2* / O70433* / Q14192* / four and a half LIM domains 2* / Four and a half LIM domains protein 2 *ENSDARG0000004201846
fhl5 / four and a half LIM domains 5 / Q5TD97* / Q9WTX7* / Four and a half LIM domains protein 5 *ENSDARG0000001480545
fhl3a / four and a half LIM domains 3a / FHL3* / Q13643* / Q9R059* / four and a half LIM domains 3* / Four and a half LIM domains protein 3 *ENSDARG0000003464344
fhl3b / four and a half LIM domains 3b / FHL3* / Q13643* / Q9R059* / four and a half LIM domains 3* / Four and a half LIM domains protein 3 *ENSDARG0000010431543
lims1 / LIM and senescent cell antigen-like domains 1 / LIMS3* / LIMS4* / P48059* / P0CW19* / P0CW20* / AC013271.1* / AC112229.3* / LIM zinc finger domain containing 4* / LIM zinc finger do...ENSDARG0000002698528
lims2 / LIM and senescent cell antigen-like domains 2 / LIMS3* / LIMS4* / LIMS1* / P48059* / P0CW19* / P0CW20* / AC013271.1* / AC112229.3* / LIM zinc finger domain containing 3* / LIM zinc ...ENSDARG0000001497626
pdlim5a / PDZ and LIM domain 5a / PDLIM5* / Q8CI51* / Q96HC4* / PDZ and LIM domain 5* / PDZ and LIM domain protein 5 *ENSDARG0000010177725
pdlim5b / PDZ and LIM domain 5b / PDLIM5* / Q96HC4* / PDZ and LIM domain 5*ENSDARG0000002760025
ldb3a / LIM domain binding 3a / LDB3* / O75112* / Q9JKS4* / LIM domain binding 3* / LIM domain-binding protein 3 *ENSDARG0000005632223
pxna / paxillin a / PXN* / P49023* / Q8VI36* / paxillin*ENSDARG0000008859022
CABZ01078593.1 / Q3TJD7* / PDLIM7* / Q9NR12* / PDZ and LIM domain 7* / PDZ and LIM domain protein 7 *ENSDARG0000010385421
pxnb / paxillin b / PXN* / P49023* / paxillin*ENSDARG0000006076621
lpxn / leupaxin / O60711* / Q99N69*ENSDARG0000007931520
ldb3b / LIM domain binding 3bENSDARG000000999745


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0055074 calcium ion homeostasis IMP
 biological_processGO:1990798 pancreas regeneration IMP
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000017 endoderm endoderm lateral region mislocalised , abnormal
endoderm increased distribution , abnormal
Show

 ZFA:0000123 liver liver decreased distribution , abnormal
Show

 ZFA:0000140 pancreas pancreas endocrine cell increased amount , abnormal
Show

 ZFA:0000254 pancreas primordium pancreas primordium increased distribution , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased mobility , abnormal
whole organism increased amount , abnormal
Show

 ZFA:0001260 endocrine pancreas endocrine pancreas pancreas induction increased occurrence , abnormal
Show

 ZFA:0001338 intestine intestine decreased distribution , abnormal
Show

 ZFA:0001370 posterior pancreatic bud posterior pancreatic bud increased distribution , abnormal
Show

 ZFA:0001390 pancreatic bud pancreatic bud endocrine cell increased distribution , abnormal
Show

 ZFA:0005162 digestive system duct digestive system duct increased distribution , abnormal
Show

 ZFA:0005654 blood plasma blood plasma calcium(2+) increased amount , abnormal
Show

 ZFA:0005754 primary islet primary islet increased distribution , abnormal
Show

 ZFA:0009101 insulin secreting cell insulin secreting cell increased amount , abnormal
insulin secreting cell increased distribution , abnormal
insulin secreting cell spatial pattern , ameliorated
Show

 ZFA:0009105 somatostatin secreting cell somatostatin secreting cell increased amount , abnormal
Show

 ZFA:0009134 insulating cell insulating cell pancreas regeneration increased rate , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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