Manteia

ENSDARG00000063370

Danio rerio

Features

Gene ID:	ENSDARG00000063370

Biological name :	sgk2a

Synonyms :	serum/glucocorticoid regulated kinase 2a / sgk2a

Possible biological names infered from orthology :	Q9HBY8 / Q9QZS5 / Serine/threonine-protein kinase Sgk2 / SGK2 / SGK2, serine/threonine kinase 2

Species:	Danio rerio

Chr. number:	23
Strand:	1
Band:
Gene start:	4324625
Gene end:	4344591

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000114309 Ensembl peptide - ENSDARP00000146578 Ensembl peptide - ENSDARP00000119396 Ensembl peptide - ENSDARP00000112790 NCBI entrez gene - 570956 See in Manteia. RefSeq - NM_001113622 RefSeq - XM_009296592 RefSeq Peptide - NP_001107094 swissprot - F1QBK0 swissprot - E9QF33 swissprot - E9QEP2 ZFIN ID - ZDB-GENE-030131-9632 Ensembl - ENSDARG00000063370

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
SGK2	ENSGALG00000003537	Gallus gallus
SGK2	ENSG00000101049	Homo sapiens
Sgk2	ENSMUSG00000017868	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
sgk1 / Q7ZTW4 / serum/glucocorticoid regulated kinase 1 / Q9WVC6* / O00141* / Serine/threonine-protein kinase Sgk1 *	ENSDARG00000025522	72
sgk3 / serum/glucocorticoid regulated kinase family, member 3 / Q96BR1* / Q9ERE3* / serum/glucocorticoid regulated kinase 3*	ENSDARG00000062460	68
si:ch211-195b13.1	ENSDARG00000016623	65
sgk2b / serum/glucocorticoid regulated kinase 2b	ENSDARG00000006598	57
akt3a / v-akt murine thymoma viral oncogene homolog 3a / AKT3* / Q9WUA6* / Q9Y243* / AKT serine/threonine kinase 3* / RAC-gamma serine/threonine-protein kinase *	ENSDARG00000104810	45
akt3b / v-akt murine thymoma viral oncogene homolog 3b	ENSDARG00000087205	44
akt2 / v-akt murine thymoma viral oncogene homolog 2 / P31751* / Q60823* / AKT serine/threonine kinase 2* / Mus musculus thymoma viral proto-onco 2 (Akt2), transcript variant 4, mRNA.*	ENSDARG00000011219	43
akt2l / v-akt murine thymoma viral oncogene homolog 2, like / AKT2* / P31751* / AKT serine/threonine kinase 2*	ENSDARG00000103612	43
prkchb / protein kinase C, eta, b / PRKCH* / P24723* / P23298* / protein kinase C eta*	ENSDARG00000043243	42
prkcea / protein kinase C, epsilon a / PRKCE* / P16054* / Q02156* / protein kinase C epsilon*	ENSDARG00000003008	41
prkceb / protein kinase C, epsilon b / PRKCE* / P16054* / Q02156* / protein kinase C epsilon*	ENSDARG00000069928	41
prkcha / protein kinase C, eta, a / PRKCH* / P24723* / P23298* / protein kinase C eta*	ENSDARG00000018382	39
prkcz / protein kinase C, zeta / Q02956* / Q05513*	ENSDARG00000043332	38
prkca / protein kinase C, alpha / P17252*	ENSDARG00000115657	38
prkci / Q90XF2 / protein kinase C, iota / P41743* / Q62074*	ENSDARG00000021225	38
prkcba / protein kinase C, beta a / PRKCB* / P68404* / P05771* / protein kinase C beta*	ENSDARG00000008723	37
prkcg / protein kinase C, gamma / P05129* / P63318*	ENSDARG00000004561	37
prkcdb / protein kinase C, delta b / PRKCD* / Q05655* / protein kinase C delta*	ENSDARG00000070651	37
prkcbb / Q7SY24 / protein kinase C, beta b / PRKCB* / P05771* / protein kinase C beta*	ENSDARG00000022254	37
PRKCA / si:ch73-374l24.1 / si:ch1073-370j18.1 / P17252* / protein kinase C alpha*	ENSDARG00000099841	37

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR000961	AGC-kinase, C-terminal
IPR008271	Serine/threonine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR017441	Protein kinase, ATP binding site
IPR017892	Protein kinase, C-terminal

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001558	regulation of cell growth	IBA
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0016310	phosphorylation	IEA
biological_process	GO:0018105	peptidyl-serine phosphorylation	IBA
biological_process	GO:0032411	positive regulation of transporter activity	IBA
biological_process	GO:0035556	intracellular signal transduction	IBA
biological_process	GO:0042127	regulation of cell proliferation	IBA
biological_process	GO:0042981	regulation of apoptotic process	IBA
cellular_component	GO:0005622	intracellular	IBA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004674	protein serine/threonine kinase activity	IBA
molecular_function	GO:0005246	calcium channel regulator activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0015459	potassium channel regulator activity	IBA
molecular_function	GO:0016301	kinase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0017080	sodium channel regulator activity	IBA
molecular_function	GO:0017081	chloride channel regulator activity	IBA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr