ENSDARG00000063535


Danio rerio

Features
Gene ID: ENSDARG00000063535
  
Biological name :chd4a
  
Synonyms : chd4a / chromodomain helicase DNA binding protein 4a
  
Possible biological names infered from orthology : CHD4 / chromodomain helicase DNA binding protein 4 / Mus musculus chromodomain helicase DNA binding protein 4 (Chd4), mRNA. / Q14839 / Q6PDQ2
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 5000885
Gene end: 5058908
  
Corresponding Affymetrix probe sets: Dr.25696.1.S1_at (Zebrafish Array)   NM_001044858_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000111640
Ensembl peptide - ENSDARP00000126227
NCBI entrez gene - 558344     See in Manteia.
RefSeq - XM_005159352
RefSeq - XM_021468085
RefSeq - NM_001044858
RefSeq Peptide - NP_001038323
swissprot - Q1LYP4
swissprot - I3ITG3
ZFIN ID - ZDB-GENE-041111-187
Ensembl - ENSDARG00000063535
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHD4ENSGALG00000013565Gallus gallus
 CHD4ENSG00000111642Homo sapiens
 Chd4ENSMUSG00000063870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chd4b / chromodomain helicase DNA binding protein 4b / CHD4* / Q14839* / Q6PDQ2* / chromodomain helicase DNA binding protein 4* / Mus musculus chromodomain helicase DNA binding protein 4 (C...ENSDARG0000002578980
chd5 / chromodomain helicase DNA binding protein 5 / A2A8L1* / Q8TDI0*ENSDARG0000010508366
chd3 / chromodomain helicase DNA binding protein 3 / Q12873*ENSDARG0000002140563
chd2 / chromodomain helicase DNA binding protein 2 / E9PZM4* / O14647* / AC013394.1*ENSDARG0000006068725
chd1 / chromodomain helicase DNA binding protein 1 / O14646* / P40201* / Q9CQS5*ENSDARG0000010378724
chd7 / chromodomain helicase DNA binding protein 7 / A2AJK6* / Q9P2D1*ENSDARG0000007521124
chd9 / chromodomain helicase DNA binding protein 9 / Q3L8U1* / Q8BYH8*ENSDARG0000007449823
chd6 / chromodomain helicase DNA binding protein 6 / Q8TD26*ENSDARG0000001724423
chd8 / chromodomain helicase DNA binding protein 8 / Q09XV5* / Q9HCK8*ENSDARG0000007554322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR000953  Chromo/chromo shadow domain
 IPR001650  Helicase, C-terminal
 IPR001965  Zinc finger, PHD-type
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR009071  High mobility group box domain
 IPR009462  Domain of unknown function DUF1086
 IPR009463  Domain of unknown function DUF1087
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR012957  CHD, C-terminal 2
 IPR012958  CHD, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016197  Chromo-like domain superfamily
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR023780  Chromo domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031101 fin regeneration IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001269 regenerating fin regenerating fin caudal fin actinotrichium disorganized , abnormal
Show

 ZFA:0001270 blastema blastema cell proliferation decreased occurrence , abnormal
Show

 ZFA:0009031 osteoblast osteoblast nucleus morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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