ENSDARG00000021405


Danio rerio

Features
Gene ID: ENSDARG00000021405
  
Biological name :chd3
  
Synonyms : chd3 / chromodomain helicase DNA binding protein 3
  
Possible biological names infered from orthology : Q12873
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 20673287
Gene end: 20758828
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127601
Ensembl peptide - ENSDARP00000147575
Ensembl peptide - ENSDARP00000148227
Ensembl peptide - ENSDARP00000150089
Ensembl peptide - ENSDARP00000155121
swissprot - X1WBL0
ZFIN ID - ZDB-GENE-121031-4
Ensembl - ENSDARG00000021405
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHD3ENSG00000170004Homo sapiens
 Chd3ENSMUSG00000018474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chd5 / chromodomain helicase DNA binding protein 5 / A2A8L1* / Q8TDI0*ENSDARG0000010508371
chd4b / chromodomain helicase DNA binding protein 4b / CHD4* / Q14839* / Q6PDQ2* / chromodomain helicase DNA binding protein 4* / Mus musculus chromodomain helicase DNA binding protein 4 (C...ENSDARG0000002578967
chd4a / chromodomain helicase DNA binding protein 4a / CHD4* / Q14839* / Q6PDQ2* / chromodomain helicase DNA binding protein 4* / Mus musculus chromodomain helicase DNA binding protein 4 (C...ENSDARG0000006353567
chd7 / chromodomain helicase DNA binding protein 7 / A2AJK6* / Q9P2D1*ENSDARG0000007521126
chd2 / chromodomain helicase DNA binding protein 2 / E9PZM4* / O14647* / AC013394.1*ENSDARG0000006068724
chd6 / chromodomain helicase DNA binding protein 6 / Q8TD26*ENSDARG0000001724424
chd9 / chromodomain helicase DNA binding protein 9 / Q3L8U1* / Q8BYH8*ENSDARG0000007449824
chd1 / chromodomain helicase DNA binding protein 1 / O14646* / P40201* / Q9CQS5*ENSDARG0000010378724
chd8 / chromodomain helicase DNA binding protein 8 / Q09XV5* / Q9HCK8*ENSDARG0000007554323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR000953  Chromo/chromo shadow domain
 IPR001650  Helicase, C-terminal
 IPR001965  Zinc finger, PHD-type
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR009071  High mobility group box domain
 IPR009462  Domain of unknown function DUF1086
 IPR009463  Domain of unknown function DUF1087
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR012957  CHD, C-terminal 2
 IPR012958  CHD, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016197  Chromo-like domain superfamily
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR023780  Chromo domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028722  Chromodomain-helicase-DNA-binding protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0007051 spindle organization IEA
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0048589 developmental growth IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016581 NuRD complex IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain edematous , abnormal
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 ZFA:0000012 central nervous system central nervous system decreased thickness , abnormal
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 ZFA:0000114 heart heart morphology , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001114 head head morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex






 

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