ENSMUSG00000018474


Mus musculus

Features
Gene ID: ENSMUSG00000018474
  
Biological name :Chd3
  
Synonyms : Chd3 / chromodomain helicase DNA binding protein 3
  
Possible biological names infered from orthology : Q12873
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B3
Gene start: 69343273
Gene end: 69369406
  
Corresponding Affymetrix probe sets: 10387316 (MoGene1.0st)   1428466_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114520
Ensembl peptide - ENSMUSP00000104301
Ensembl peptide - ENSMUSP00000118172
Ensembl peptide - ENSMUSP00000122137
Ensembl peptide - ENSMUSP00000121192
Ensembl peptide - ENSMUSP00000090649
NCBI entrez gene - 216848     See in Manteia.
MGI - MGI:1344395
RefSeq - XM_017314456
RefSeq - XM_006532885
RefSeq - XM_006532886
RefSeq - XM_006532887
RefSeq - XM_006532888
RefSeq - XM_006532889
RefSeq - XM_006532890
RefSeq - XM_017314455
RefSeq - NM_146019
RefSeq - XM_006532880
RefSeq - XM_006532881
RefSeq - XM_006532882
RefSeq - XM_006532883
RefSeq - XM_006532884
RefSeq Peptide - NP_666131
swissprot - B1AR17
swissprot - F6V4V3
swissprot - E9Q614
swissprot - B0QZH8
swissprot - B0QZH7
swissprot - F7C528
Ensembl - ENSMUSG00000018474
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chd3ENSDARG00000021405Danio rerio
 CHD3ENSG00000170004Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chd5 / A2A8L1 / Chromodomain-helicase-DNA-binding protein 5 / Q8TDI0*ENSMUSG0000000504567
Chd4 / Q6PDQ2 / Mus musculus chromodomain helicase DNA binding protein 4 (Chd4), mRNA. / Q14839* / chromodomain helicase DNA binding protein 4*ENSMUSG0000006387064
Chd7 / A2AJK6 / Chromodomain-helicase-DNA-binding protein 7 / Q9P2D1*ENSMUSG0000004123525
Chd9 / Q8BYH8 / Chromodomain-helicase-DNA-binding protein 9 / Q3L8U1*ENSMUSG0000005660824
Chd6 / A3KFM7 / Chromodomain-helicase-DNA-binding protein 6 / Q8TD26*ENSMUSG0000005713324
Chd2 / E9PZM4 / Chromodomain-helicase-DNA-binding protein 2 / O14647*ENSMUSG0000007867124
Chd8 / Q09XV5 / Chromodomain-helicase-DNA-binding protein 8 / Q9HCK8*ENSMUSG0000005375423
Chd1 / P40201 / Q9CQS5 / Chromodomain-helicase-DNA-binding protein 1 / O14646*ENSMUSG0000002385223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR000953  Chromo/chromo shadow domain
 IPR001650  Helicase, C-terminal
 IPR001965  Zinc finger, PHD-type
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR009462  Domain of unknown function DUF1086
 IPR009463  Domain of unknown function DUF1087
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR012957  CHD, C-terminal 2
 IPR012958  CHD, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016197  Chromo-like domain superfamily
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR023780  Chromo domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028722  Chromodomain-helicase-DNA-binding protein 3
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006333 chromatin assembly or disassembly IDA
 biological_processGO:0007051 spindle organization ISO
 biological_processGO:0007098 centrosome cycle ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005815 microtubule organizing center ISO
 cellular_componentGO:0016581 NuRD complex ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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