ENSMUSG00000057133


Mus musculus

Features
Gene ID: ENSMUSG00000057133
  
Biological name :Chd6
  
Synonyms : A3KFM7 / Chd6 / Chromodomain-helicase-DNA-binding protein 6
  
Possible biological names infered from orthology : Q8TD26
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H2
Gene start: 160946978
Gene end: 161109075
  
Corresponding Affymetrix probe sets: 10489266 (MoGene1.0st)   1427384_at (Mouse Genome 430 2.0 Array)   1431047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042291
Ensembl peptide - ENSMUSP00000123240
Ensembl peptide - ENSMUSP00000117075
NCBI entrez gene - 71389     See in Manteia.
MGI - MGI:1918639
RefSeq - XM_017319259
RefSeq - XM_006500184
RefSeq - XM_011239776
RefSeq - XM_011239777
RefSeq - XM_017319258
RefSeq - NM_173368
RefSeq Peptide - NP_775544
swissprot - A3KFM7
swissprot - A3KFM6
swissprot - A3KFM8
Ensembl - ENSMUSG00000057133
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chd6ENSDARG00000017244Danio rerio
 ENSGALG00000032417Gallus gallus
 CHD6ENSG00000124177Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chd7 / A2AJK6 / Chromodomain-helicase-DNA-binding protein 7 / Q9P2D1*ENSMUSG0000004123546
Chd9 / Q8BYH8 / Chromodomain-helicase-DNA-binding protein 9 / Q3L8U1*ENSMUSG0000005660843
Chd8 / Q09XV5 / Chromodomain-helicase-DNA-binding protein 8 / Q9HCK8*ENSMUSG0000005375440
Chd5 / A2A8L1 / Chromodomain-helicase-DNA-binding protein 5 / Q8TDI0*ENSMUSG0000000504518
Chd3 / chromodomain helicase DNA binding protein 3 / Q12873*ENSMUSG0000001847418
Chd4 / Q6PDQ2 / Mus musculus chromodomain helicase DNA binding protein 4 (Chd4), mRNA. / Q14839* / chromodomain helicase DNA binding protein 4*ENSMUSG0000006387017
Chd2 / E9PZM4 / Chromodomain-helicase-DNA-binding protein 2 / O14647*ENSMUSG0000007867116
Chd1 / P40201 / Q9CQS5 / Chromodomain-helicase-DNA-binding protein 1 / O14646*ENSMUSG0000002385215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR000953  Chromo/chromo shadow domain
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR006576  BRK domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016197  Chromo-like domain superfamily
 IPR023780  Chromo domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001221 transcription cofactor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016817 hydrolase activity, acting on acid anhydrides IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Chrna3tm1.1Hwrt/Chrna3tm1.1Hwrt
Genetic Background: B6.129S7-Chrna3tm1.1Hwrt

Allelic Composition: Chd6tm1.2Fier/Chd6tm1.2Fier
Genetic Background: 129S1/SvImJ-Chd6tm1.2Fier

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chrna3tm1.1Hwrt/Chrna3tm1.1Hwrt
Genetic Background: B6.129S7-Chrna3tm1.1Hwrt

 MP:0002797 thigmotaxis "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814]
Show

Allelic Composition: Chrna3tm1.1Hwrt/Chrna3tm1.1Hwrt
Genetic Background: B6.129S7-Chrna3tm1.1Hwrt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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