Manteia

ENSDARG00000074908

Danio rerio

Features

Gene ID:	ENSDARG00000074908

Biological name :	col6a1

Synonyms :	col6a1 / collagen, type VI, alpha 1

Possible biological names infered from orthology :	Collagen alpha-1(VI) chain / collagen type VI alpha 1 chain / P12109 / Q04857

Species:	Danio rerio

Chr. number:	11
Strand:	-1
Band:
Gene start:	33996526
Gene end:	34065718

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000103794 NCBI entrez gene - 569755 See in Manteia. RefSeq - XM_009306169 swissprot - F1Q6P3 ZFIN ID - ZDB-GENE-070501-6 Ensembl - ENSDARG00000074908

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
COL6A1	ENSGALG00000005974	Gallus gallus
COL6A1	ENSG00000142156	Homo sapiens
Col6a1	ENSMUSG00000001119	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
col6a2 / collagen, type VI, alpha 2 / P12110* / Q02788* / collagen type VI alpha 2 chain* / Mus musculus collagen, type VI, alpha 2 (Col6a2), transcript variant 2, mRNA.*	ENSDARG00000061436	34
col28a1a / collagen, type XXVIII, alpha 1a / Q2UY11* / Q2UY09* / COL28A1* / Collagen alpha-1(XXVIII) chain * / collagen type XXVIII alpha 1 chain*	ENSDARG00000077084	26
col28a1b / collagen, type XXVIII, alpha 1b / Q2UY09* / COL28A1* / collagen type XXVIII alpha 1 chain*	ENSDARG00000087087	26
col28a2a / collagen, type XXVIII, alpha 2a	ENSDARG00000076321	26
col28a2b / collagen, type XXVIII, alpha 2b	ENSDARG00000100781	25
col17a1b / collagen, type XVII, alpha 1b / Q9UMD9* / Q07563* / COL17A1* / collagen type XVII alpha 1 chain* / Collagen alpha-1(XVII) chain 120 kDa linear IgA disease antigen homolog*	ENSDARG00000079011	18
col17a1a / collagen, type XVII, alpha 1a / Q9UMD9* / Q07563* / COL17A1* / collagen type XVII alpha 1 chain* / Collagen alpha-1(XVII) chain 120 kDa linear IgA disease antigen homolog*	ENSDARG00000069415	16
A5PMY6 / colec12 / collectin sub-family member 12 / Q8K4Q8* / Q5KU26* / Collectin-12 * / collectin subfamily member 12*	ENSDARG00000061140	13
wu:fc38h03	ENSDARG00000074216	11
colq / collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase / O35348* / Q9Y215* / Acetylcholinesterase collagenic tail peptide * / collagen like tail ...	ENSDARG00000019692	11
scara3 / scavenger receptor class A, member 3 / Q6AZY7*	ENSDARG00000008060	8

Protein motifs (from Interpro)

Interpro ID	Name
IPR002035	von Willebrand factor, type A
IPR008160	Collagen triple helix repeat

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007519	skeletal muscle tissue development	IMP
biological_process	GO:0007626	locomotory behavior	IMP
biological_process	GO:0061061	muscle structure development	IMP

Pathways (from Reactome)

Pathway description

Collagen degradation

Collagen biosynthesis and modifying enzymes

Signaling by PDGF

Assembly of collagen fibrils and other multimeric structures

Integrin cell surface interactions

ECM proteoglycans

NCAM1 interactions

Collagen chain trimerization

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000054	pericardium	pericardium edematous , abnormal	Show
ZFA:0001056	myotome	myotome muscle tendon junction structure , abnormal	Show
ZFA:0001094	whole organism	whole organism decreased size , abnormal whole organism paralysed , abnormal whole organism decreased mobility , abnormal whole organism hypoplastic , abnormal	Show
ZFA:0001115	trunk	trunk bent , abnormal	Show
ZFA:0001117	post-vent region	post-vent region bent , abnormal	Show
ZFA:0005145	muscle	muscle muscle tendon junction morphology , abnormal muscle muscle tendon junction disorganized , abnormal muscle myofibril disorganized , abnormal muscle T-tubule dilated , abnormal	Show
ZFA:0005277	skeletal muscle	skeletal muscle morphology , abnormal skeletal muscle refractivity , abnormal skeletal muscle collagenous , abnormal skeletal muscle muscle cell disorganized , abnormal	Show
ZFA:0009114	muscle cell	muscle cell mitochondrion increased size , abnormal muscle cell mitochondrion aggregated , abnormal muscle cell mitochondrial intermembrane space dilated , abnormal muscle cell myofibril separated from muscle cell muscle tendon junction, abnormal muscle cell myofibril misaligned with muscle cell myofibril, abnormal muscle cell myofibril kinked , abnormal muscle cell mitochondrial crista decreased amount , abnormal muscle cell apoptotic , abnormal muscle cell nucleus increased amount , abnormal muscle cell mitochondrion morphology , abnormal muscle cell mitochondrial outer membrane detached from muscle cell mitochondrial inner membrane, abnormal muscle cell mitochondrial matrix morphology , abnormal muscle cell vacuole present , abnormal muscle cell sarcoplasmic reticulum increased size , abnormal muscle cell sarcomere misaligned with muscle cell sarcomere, abnormal muscle cell mitochondrial crista morphology , abnormal muscle cell mitochondrial crista swollen , abnormal muscle cell skeletal muscle myofibril disorganized , abnormal muscle cell sarcoplasm composition , abnormal	Show
ZFA:0009115	skeletal muscle cell	skeletal muscle cell endoplasmic reticulum dilated , abnormal skeletal muscle cell sarcolemma structure , abnormal skeletal muscle cell collagen trimer spatial pattern , abnormal skeletal muscle cell mitochondrion increased amount , abnormal skeletal muscle cell mitochondrion swollen , abnormal skeletal muscle cell myofibril structure , abnormal skeletal muscle cell mitochondrial crista structure , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr