ENSDARG00000075625


Danio rerio

Features
Gene ID: ENSDARG00000075625
  
Biological name :lrig1
  
Synonyms : leucine-rich repeats and immunoglobulin-like domains 1 / lrig1
  
Possible biological names infered from orthology : Leucine-rich repeats and immunoglobulin-like domains protein 1 / P70193 / Q96JA1
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 16329776
Gene end: 16395956
  
Corresponding Affymetrix probe sets: Dr.17817.1.A1_at (Zebrafish Array)   XM_683725_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000138833
Ensembl peptide - ENSDARP00000147892
Ensembl peptide - ENSDARP00000147144
Ensembl peptide - ENSDARP00000141913
Ensembl peptide - ENSDARP00000098283
NCBI entrez gene - 560325     See in Manteia.
RefSeq - XM_683725
swissprot - E7EZ01
swissprot - A0A0R4ISI1
swissprot - A0A0J9YJN0
ZFIN ID - ZDB-GENE-031113-23
Ensembl - ENSDARG00000075625
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRIG1ENSGALG00000007483Gallus gallus
 LRIG1ENSG00000144749Homo sapiens
 Lrig1ENSMUSG00000030029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrig2 / leucine-rich repeats and immunoglobulin-like domains 2 / O94898* / Q52KR2*ENSDARG0000007856143
adgra2 / E7FBY6 / adhesion G protein-coupled receptor A2 / Q91ZV8* / Q96PE1*ENSDARG0000007699415
vasna / vasorin a / VASN* / Q6EMK4* / vasorin*ENSDARG0000009926613
vasnb / vasorin b / VASN* / Q9CZT5* / Q6EMK4* / vasorin*ENSDARG0000010256513
lgi3 / leucine-rich repeat LGI family, member 3 / Q8K406* / Q8N145*ENSDARG0000004135810
lgi2a / leucine-rich repeat LGI family, member 2a / LGI2* / Q8N0V4* / leucine rich repeat LGI family member 2*ENSDARG0000011106910
lgi1a / leucine-rich, glioma inactivated 1a / LGI4* / Q8N135* / leucine rich repeat LGI family member 4*ENSDARG0000002049310
lgi1b / leucine-rich, glioma inactivated 1b / LGI4* / Q8K1S1* / Q8N135* / leucine rich repeat LGI family member 4*ENSDARG0000005842110
lgi2b / leucine-rich repeat LGI family, member 2b / LGI2* / Q8K4Z0* / Q8N0V4* / leucine rich repeat LGI family member 2*ENSDARG000000697019
adgra3 / adhesion G protein-coupled receptor A3 / Q8IWK6*ENSDARG000000736737
adgra1a / adhesion G protein-coupled receptor A1aENSDARG000000541775


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Negative regulation of MET activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000063719 usp8 / ubiquitin specific peptidase 8 / P40818* / Q80U87*  / reaction
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex / reaction






 

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