ENSDARG00000077403


Danio rerio

Features
Gene ID: ENSDARG00000077403
  
Biological name :col8a1a
  
Synonyms : col8a1a / collagen, type VIII, alpha 1a
  
Possible biological names infered from orthology : COL8A1 / Collagen alpha-1(VIII) chain Vastatin / collagen type VIII alpha 1 chain / P27658 / Q00780
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 30090656
Gene end: 30102778
  
Corresponding Affymetrix probe sets: Dr.20245.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000093755
NCBI entrez gene - 557795     See in Manteia.
RefSeq - NM_001142374
RefSeq Peptide - NP_001135846
swissprot - B0S5W0
ZFIN ID - ZDB-GENE-070912-274
Ensembl - ENSDARG00000077403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL8A1ENSGALG00000015253Gallus gallus
 COL8A1ENSG00000144810Homo sapiens
 Col8a1ENSMUSG00000068196Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
col8a1b / collagen, type VIII, alpha 1b / COL8A1* / P27658* / Q00780* / collagen type VIII alpha 1 chain* / Collagen alpha-1(VIII) chain Vastatin*ENSDARG0000000353363
col8a2 / collagen, type VIII, alpha 2 / P25318* / P25067* / Collagen alpha-2(VIII) chain * / collagen type VIII alpha 2 chain*ENSDARG0000006089349
col10a1b / collagen, type X, alpha 1b / Q03692* / COL10A1* / collagen type X alpha 1 chain*ENSDARG0000010153546
col10a1a / collagen, type X, alpha 1a / Q05306* / Q03692* / COL10A1* / Collagen alpha-1(X) chain * / collagen type X alpha 1 chain*ENSDARG0000005475345
A5PN28 / otol1a / otolin 1a / OTOL1* / Q4ZJM7* / A6NHN0* / otolin 1*ENSDARG0000000177122
otol1b / otolin 1b / OTOL1* / A6NHN0* / Q4ZJM7* / otolin 1*ENSDARG0000005896022
CABZ01067232.1ENSDARG0000005740821
c1qtnf9 / C1q and TNF related 9 / B2RNN3* / P0C862* / C1QTNF9B* / C1q and TNF related 9B*ENSDARG0000005831819
c1qtnf2 / C1q and TNF related 2 / Q9BXJ5* / Q9D8U4* / Complement C1q tumor necrosis factor-related protein 2 *ENSDARG0000005994414
c1qtnf7 / C1q and TNF related 7 / Q9BXJ2*ENSDARG0000007494914
adipoqb / adiponectin, C1Q and collagen domain containing, b / Q60994* / ADIPOQ* / Q15848* / Adiponectin * / adiponectin, C1Q and collagen domain containing*ENSDARG0000010008613
adipoqa / adiponectin, C1Q and collagen domain containing, a / Q60994* / ADIPOQ* / Q15848* / Adiponectin * / adiponectin, C1Q and collagen domain containing*ENSDARG0000006222812
c1qtnf5 / C1q and TNF related 5 / Q8K479* / Q9BXJ0* / Complement C1q tumor necrosis factor-related protein 5 *ENSDARG0000005613411
c1qc / complement component 1, q subcomponent, C chain / P02747* / Q02105* / complement C1q C chain* / Complement C1q subcomponent subunit C *ENSDARG0000009562711
c1qb / complement component 1, q subcomponent, B chain / P02746* / P14106* / complement C1q B chain* / Complement C1q subcomponent subunit B *ENSDARG000000446129


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008160  Collagen triple helix repeat
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014028 notochord formation IMP
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0048570 notochord morphogenesis IMP
 biological_processGO:0060322 head development IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000031 hypochord hypochord rough endoplasmic reticulum increased size , abnormal
Show

 ZFA:0000106 extension extension decreased length , abnormal
Show

 ZFA:0000126 centrum centrum irregular spatial pattern , abnormal
centrum malformed , abnormal
centrum disorganized , abnormal
centrum fused with centrum , abnormal
Show

 ZFA:0000135 notochord notochord quality , abnormal
notochord deformed , abnormal
notochord undulate , abnormal
notochord bent , abnormal
notochord morphology , abnormal
notochord rough endoplasmic reticulum increased size , abnormal
notochord kinked , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism axis shortened , abnormal
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 ZFA:0001114 head head malformed , abnormal
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 ZFA:0001189 vertebra vertebra fused with vertebra , abnormal
vertebra malformed , abnormal
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 ZFA:0001559 vertebral column vertebral column deviation , abnormal
vertebral column osteoblast mislocalised , abnormal
Show

 ZFA:0005744 notochord outer sheath cell notochord outer sheath cell disorganized , abnormal
notochord outer sheath cell deformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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