ENSDARG00000077842


Danio rerio

Features
Gene ID: ENSDARG00000077842
  
Biological name :ajuba
  
Synonyms : ajuba / ajuba LIM protein
  
Possible biological names infered from orthology : LIM domain-containing protein ajuba / Q91XC0 / Q96IF1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 24100155
Gene end: 24112484
  
Corresponding Affymetrix probe sets: Dr.5872.1.A1_at (Zebrafish Array)   XM_696274_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000100146
NCBI entrez gene - 572549     See in Manteia.
RefSeq - XM_696274
swissprot - E7FFI0
ZFIN ID - ZDB-GENE-030131-9341
Ensembl - ENSDARG00000077842
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AJUBAENSG00000129474Homo sapiens
 AjubaENSMUSG00000022178Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wtip / A8DZE6 / WT1 interacting protein / A6NIX2* / Q7TQJ8*ENSDARG0000010360729
lpp / LIM domain containing preferred translocation partner in lipoma / Q8BFW7* / Q93052* / Lipoma-preferred partner homolog *ENSDARG0000002357817
zyx / zyxin / Q15942* / Q62523*ENSDARG0000007573316
trip6 / thyroid hormone receptor interactor 6 / Q15654* / Q9Z1Y4*ENSDARG0000006933115
CABZ01043952.1 / LIMD1* / Q9UGP4* / LIM domains containing 1*ENSDARG0000011095411
fblim1 / filamin binding LIM protein 1 / Q71FD7* / Q8WUP2*ENSDARG0000007155810
ablim2 / actin binding LIM protein family, member 2 / Q6H8Q1* / Q8BL65* / actin-binding LIM protein 2*ENSDARG000000552238
ablim1a / actin binding LIM protein 1a / ABLIM1* / O14639* / Q8K4G5* / actin binding LIM protein 1*ENSDARG000000601498
ablim3 / actin binding LIM protein family, member 3 / O94929* / Q69ZX8*ENSDARG000000881688
ablim1b / actin binding LIM protein 1b / ABLIM1* / O14639* / Q8K4G5* / actin binding LIM protein 1*ENSDARG000000450646
BX465198.3 / DMTN* / Q08495* / dematin actin binding protein*ENSDARG000001164843
dmtn / dematin actin binding protein / Q08495* / Q9WV69* / Dematin *ENSDARG000000131102


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0007010 cytoskeleton organization IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0035329 hippo signaling IBA
 biological_processGO:0035331 negative regulation of hippo signaling IBA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 biological_processGO:2000637 positive regulation of gene silencing by miRNA IBA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005911 cell-cell junction IBA
 cellular_componentGO:0005912 adherens junction IBA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Regulation of PLK1 Activity at G2/M Transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle cardiac muscle cell increased amount , abnormal
Show

 ZFA:0000028 heart primordium heart primordium increased distribution , abnormal
heart primordium decreased distribution , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart increased size , abnormal
Show

 ZFA:0000471 atrium atrium orientation cardiac ventricle , abnormal
atrium cardiac muscle cell increased amount , abnormal
Show

 ZFA:0005041 anterior lateral plate mesoderm anterior lateral plate mesoderm increased distribution , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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