ENSDARG00000099175


Danio rerio

Features
Gene ID: ENSDARG00000099175
  
Biological name :hmgb1a
  
Synonyms : high mobility group box 1a / hmgb1a
  
Possible biological names infered from orthology : high mobility group box 1 / High mobility group protein B1 / HMGB1 / P09429 / P63158
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 36026576
Gene end: 36032038
  
Corresponding Affymetrix probe sets: Dr.1067.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134229
Ensembl peptide - ENSDARP00000153427
NCBI entrez gene - 321622     See in Manteia.
NCBI entrez gene - 110438871     See in Manteia.
RefSeq - XM_021472359
RefSeq Peptide - NP_955849
swissprot - Q6NX86
ZFIN ID - ZDB-GENE-030131-341
Ensembl - ENSDARG00000099175
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMGB1ENSGALG00000042875Gallus gallus
 HMGB1ENSG00000189403Homo sapiens
 Hmgb1ENSMUSG00000066551Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hmgb1b / high mobility group box 1b / HMGB1* / P09429* / P63158* / high mobility group box 1* / High mobility group protein B1 *ENSDARG0000003047977
hmgb2a / high mobility group box 2a / HMGB2* / P26583* / P30681* / high mobility group box 2* / High mobility group protein B2 *ENSDARG0000002972271
hmgb2b / high mobility group box 2bENSDARG0000005399063
hmgb3b / high mobility group box 3b / HMGB3* / O15347* / O54879* / high mobility group box 3* / High mobility group protein B3 *ENSDARG0000000640861
hmgb3a / high mobility group box 3a / HMGB3* / O15347* / O54879* / high mobility group box 3* / High mobility group protein B3 *ENSDARG0000005672560


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR017967  HMG box A DNA-binding domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009409 response to cold IDA
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0031099 regeneration IMP
 biological_processGO:0031103 axon regeneration IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Activation of DNA fragmentation factor
Regulation of TLR by endogenous ligand
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased width , abnormal
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 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
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 ZFA:0000107 eye eye decreased distance eye , abnormal
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 ZFA:0000109 forebrain forebrain neuromere disheveled , abnormal
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 ZFA:0000135 notochord notochord undulate , abnormal
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 ZFA:0000161 third ventricle third ventricle compartment boundary inconspicuous , abnormal
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 ZFA:0001094 whole organism whole organism immobile , abnormal
whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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