ENSDARG00000099637


Danio rerio

Features
Gene ID: ENSDARG00000099637
  
Biological name :szl
  
Synonyms : sizzled / szl
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 371164
Gene end: 375882
  
Corresponding Affymetrix probe sets: Dr.25497.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000133257
NCBI entrez gene - 353294     See in Manteia.
swissprot - Q7SX78
ZFIN ID - ZDB-GENE-030530-1
Ensembl - ENSDARG00000099637
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000008635Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FP102169.1ENSDARG0000011096737
sfrp2 / secreted frizzled-related protein 2 / P97299* / Q96HF1*ENSDARG0000007005032
sfrp5 / secreted frizzled-related protein 5 / Q5T4F7* / secreted frizzled-related sequence protein 5*ENSDARG0000003904129
sfrp1a / secreted frizzled-related protein 1a / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*ENSDARG0000003552129
sfrp1b / secreted frizzled-related protein 1b / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*ENSDARG0000005767827
CZQB01095947.1ENSDARG0000008956326
fzd10 / frizzled class receptor 10 / Q8BKG4* / Q9ULW2* / Frizzled-10 *ENSDARG0000006821323
fzd1 / frizzled class receptor 1 / Q9UP38*ENSDARG0000010606223
fzd5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSDARG0000002542022
fzd9a / frizzled class receptor 9a / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000003518522
fzd2 / frizzled class receptor 2 / Q14332* / Q9JIP6* / Frizzled-2 *ENSDARG0000005443822
fzd3b / frizzled class receptor 3bENSDARG0000005869222
fzd9b / frizzled class receptor 9b / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000001467322
fzd7a / frizzled class receptor 7a / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000006000422
fzd8a / frizzled class receptor 8a / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000004544421
fzd3a / frizzled class receptor 3a / FZD3* / Q61086* / Q9NPG1* / Frizzled-3 * / frizzled class receptor 3*ENSDARG0000002166421
fzd8b / frizzled class receptor 8b / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000003856921
fzd7b / frizzled class receptor 7b / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000002758921
CABZ01088508.1 / FZD6* / O60353* / frizzled class receptor 6*ENSDARG0000010487419
frzb / frizzled related protein / P97401* / Q92765* / Secreted frizzled-related protein 3 *ENSDARG0000001838317


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR020067  Frizzled domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048263 determination of dorsal identity IMP
 biological_processGO:0050821 protein stabilization IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000040 median fin fold median fin fold duplicated , abnormal
Show

 ZFA:0000077 tail bud tail bud increased thickness , abnormal
Show

 ZFA:0000106 extension extension increased size , abnormal
extension wholly ventralized , abnormal
Show

 ZFA:0000108 fin fin mislocalised , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm increased width , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0001058 caudal fin caudal fin duplicated , abnormal
caudal fin multiple , abnormal
caudal fin increased amount , abnormal
Show

 ZFA:0001069 ventral fin fold ventral fin fold duplicated , abnormal
ventral fin fold increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region quality , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased size , abnormal
Show

 ZFA:0001162 anal fin anal fin duplicated , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
Show

 ZFA:0005222 ventral larval melanophore stripe ventral larval melanophore stripe duplicated , abnormal
Show

 ZFA:0009091 melanocyte melanocyte irregular spatial pattern , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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