ENSDARG00000106062


Danio rerio

Features
Gene ID: ENSDARG00000106062
  
Biological name :fzd1
  
Synonyms : frizzled class receptor 1 / fzd1
  
Possible biological names infered from orthology : Frizzled-1 / O70421 / Q9UP38
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 53917415
Gene end: 53919115
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147690
NCBI entrez gene - 557384     See in Manteia.
RefSeq - NM_001130614
RefSeq Peptide - NP_001124086
swissprot - B3DJ49
ZFIN ID - ZDB-GENE-990415-219
Ensembl - ENSDARG00000106062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FZD1ENSGALG00000009064Gallus gallus
 FZD1ENSG00000157240Homo sapiens
 Fzd1ENSMUSG00000044674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fzd7a / frizzled class receptor 7a / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000006000477
fzd7b / frizzled class receptor 7b / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000002758977
fzd2 / frizzled class receptor 2 / Q14332* / Q9JIP6* / Frizzled-2 *ENSDARG0000005443874
fzd8a / frizzled class receptor 8a / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000004544452
fzd5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSDARG0000002542049
fzd8b / frizzled class receptor 8b / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000003856948
fzd10 / frizzled class receptor 10 / Q8BKG4* / Q9ULW2* / Frizzled-10 *ENSDARG0000006821346
fzd9a / frizzled class receptor 9a / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000003518544
fzd9b / frizzled class receptor 9b / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000001467344
fzd3b / frizzled class receptor 3bENSDARG0000005869243
fzd3a / frizzled class receptor 3a / FZD3* / Q61086* / Q9NPG1* / Frizzled-3 * / frizzled class receptor 3*ENSDARG0000002166442
CABZ01088508.1 / FZD6* / O60353* / frizzled class receptor 6*ENSDARG0000010487438
smo / smoothened, frizzled class receptor / P56726* / Q99835*ENSDARG0000000295225
sfrp5 / secreted frizzled-related protein 5 / Q5T4F7* / secreted frizzled-related sequence protein 5*ENSDARG0000003904116
sfrp1a / secreted frizzled-related protein 1a / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*ENSDARG0000003552114
sfrp2 / secreted frizzled-related protein 2 / P97299* / Q96HF1*ENSDARG0000007005014
sfrp1b / secreted frizzled-related protein 1b / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*ENSDARG0000005767814
frzb / frizzled related protein / P97401* / Q92765* / Secreted frizzled-related protein 3 *ENSDARG0000001838314
CZQB01095947.1ENSDARG0000008956313
FP102169.1ENSDARG0000011096713


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
PCP/CE pathway
Asymmetric localization of PCP proteins
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000055554 wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*  / complex
 ENSDARG00000052468 si:dkeyp-80c12.7 / GSK3B (1 of many) / GSK3B* / P49841* / Q9WV60* / glycogen synthase kinase 3 beta*  / complex / reaction
 ENSDARG00000102964 axin1 / O15169*  / complex / reaction
 ENSDARG00000017803 gsk3b / glycogen synthase kinase 3 beta / P49841* / Q9WV60*  / complex / reaction
 ENSDARG00000010515 dvl1a / dishevelled segment polarity protein 1a / DVL1* / P51141* / O14640* / Segment polarity DVL-1 * / dishevelled segment polarity protein 1*  / complex
 ENSDARG00000055552 dvl1b / dishevelled segment polarity protein 1b / DVL1* / P51141* / O14640* / Segment polarity DVL-1 * / dishevelled segment polarity protein 1*  / complex
 ENSDARG00000014796 wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*  / complex






 

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