ENSGALG00000009064


Gallus gallus

Features
Gene ID: ENSGALG00000009064
  
Biological name :FZD1
  
Synonyms : frizzled-1 precursor / FZD1
  
Possible biological names infered from orthology : Frizzled-1 / frizzled class receptor 1 / O70421 / Q9UP38
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 22162541
Gene end: 22164687
  
Corresponding Affymetrix probe sets: Gga.4087.1.S1_at (Chicken Array)   Gga.4087.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058377
Ensembl peptide - ENSGALP00000014736
NCBI entrez gene - 374062     See in Manteia.
RefSeq - NM_001030337
RefSeq Peptide - NP_001025508
swissprot - F1NGQ9
swissprot - A0A1D5PZG4
Ensembl - ENSGALG00000009064
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fzd1ENSDARG00000106062Danio rerio
 FZD1ENSG00000157240Homo sapiens
 Fzd1ENSMUSG00000044674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497379
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084777
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410150
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200347
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999946
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192745
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265245
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230843
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724242
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062639
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611424
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199715
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276314
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG0000000924113
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347313
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751513
crescent precursor ENSGALG0000000694412
ENSGALG0000000863510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain
 IPR026548  Frizzled-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0003149 membranous septum morphogenesis IEA
 biological_processGO:0003150 muscular septum morphogenesis IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0035425 autocrine signaling IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation IEA
 biological_processGO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0060022 hard palate development IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IEA
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Asymmetric localization of PCP proteins
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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