ENSGALG00000042308


Gallus gallus

Features
Gene ID: ENSGALG00000042308
  
Biological name :FZD3
  
Synonyms : frizzled class receptor 3 / FZD3
  
Possible biological names infered from orthology : Frizzled-3 / Q61086 / Q9NPG1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 106289859
Gene end: 106341933
  
Corresponding Affymetrix probe sets: Gga.3839.1.S1_s_at (Chicken Array)   Gga.7379.1.S1_at (Chicken Array)   GgaAffx.10643.1.S1_s_at (Chicken Array)   GgaAffx.25017.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043647
NCBI entrez gene - 395572     See in Manteia.
RefSeq - NM_001271940
RefSeq - NM_001271941
RefSeq Peptide - NP_001258870
RefSeq Peptide - NP_001258869
swissprot - A0A1D5NTJ0
Ensembl - ENSGALG00000042308
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fzd3aENSDARG00000021664Danio rerio
 FZD3ENSG00000104290Homo sapiens
 Fzd3ENSMUSG00000007989Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062652
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497336
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906435
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084734
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410131
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192730
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200330
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999930
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265228
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724226
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611422
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199711
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276310
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347310
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG000000075159
crescent precursor ENSGALG000000069449
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG000000092419
ENSGALG000000086358


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain
 IPR026553  Frizzled-3, vertebrates


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001736 establishment of planar polarity IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0033278 cell proliferation in midbrain IEA
 biological_processGO:0036342 post-anal tail morphogenesis IEA
 biological_processGO:0036514 dopaminergic neuron axon guidance IEA
 biological_processGO:0036515 serotonergic neuron axon guidance IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0045976 negative regulation of mitotic cell cycle, embryonic IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:0071679 commissural neuron axon guidance IEA
 biological_processGO:1900118 negative regulation of execution phase of apoptosis IEA
 biological_processGO:1904938 planar cell polarity pathway involved in axon guidance IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032433 filopodium tip IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ pathway
Asymmetric localization of PCP proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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