ENSGALG00000034973


Gallus gallus

Features
Gene ID: ENSGALG00000034973
  
Biological name :FZD7
  
Synonyms : frizzled class receptor 7 / FZD7
  
Possible biological names infered from orthology : Frizzled-7 / O75084 / Q61090
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 11734619
Gene end: 11737069
  
Corresponding Affymetrix probe sets: Gga.110.1.S1_at (Chicken Array)   Gga.110.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051203
Ensembl peptide - ENSGALP00000058488
swissprot - A0A1D5PEJ9
swissprot - A0A1D5PZS2
Ensembl - ENSGALG00000034973
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fzd7aENSDARG00000060004Danio rerio
 fzd7bENSDARG00000027589Danio rerio
 FZD7ENSG00000155760Homo sapiens
 Fzd7ENSMUSG00000041075Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906474
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084772
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410147
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999944
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200343
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265242
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192742
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230840
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724239
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062637
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611422
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199715
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276314
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347314
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751513
crescent precursor ENSGALG0000000694412
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG0000000924111
ENSGALG0000000863511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain
 IPR026552  Frizzled-7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010812 negative regulation of cell-substrate adhesion IEA
 biological_processGO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0035567 non-canonical Wnt signaling pathway IEA
 biological_processGO:0038031 non-canonical Wnt signaling pathway via JNK cascade IEA
 biological_processGO:0042327 positive regulation of phosphorylation IEA
 biological_processGO:0042666 negative regulation of ectodermal cell fate specification IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048103 somatic stem cell division IEA
 biological_processGO:0060054 positive regulation of epithelial cell proliferation involved in wound healing IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060231 mesenchymal to epithelial transition IEA
 biological_processGO:2000726 negative regulation of cardiac muscle cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Asymmetric localization of PCP proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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