ENSGALG00000031997


Gallus gallus

Features
Gene ID: ENSGALG00000031997
  
Biological name :SFRP4
  
Synonyms : secreted frizzled related protein 4 / SFRP4
  
Possible biological names infered from orthology : Q6FHJ7 / Q9Z1N6
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 46310717
Gene end: 46320326
  
Corresponding Affymetrix probe sets: Gga.7890.1.S1_at (Chicken Array)   GgaAffx.23775.1.S1_at (Chicken Array)   GgaAffx.23775.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046731
Ensembl peptide - ENSGALP00000053414
Ensembl peptide - ENSGALP00000048968
NCBI entrez gene - 420732     See in Manteia.
RefSeq - XM_015281688
RefSeq - XM_015281689
swissprot - A0A1D5PKQ3
swissprot - A0A1D5P8C2
swissprot - A0A1D5P237
Ensembl - ENSGALG00000031997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SFRP4ENSG00000106483Homo sapiens
 Sfrp4ENSMUSG00000021319Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276346
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999923
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497323
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410123
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906423
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192722
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084721
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200320
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062619
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230819
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724219
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611417
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265217
ENSGALG0000000863515
crescent precursor ENSGALG0000000694414
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347314
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751513
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG0000000924111


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR018933  Netrin module, non-TIMP type
 IPR020067  Frizzled domain
 IPR026560  Secreted frizzled-related protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002092 positive regulation of receptor internalization IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030510 regulation of BMP signaling pathway IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045606 positive regulation of epidermal cell differentiation IEA
 biological_processGO:0055062 phosphate ion homeostasis IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1902174 positive regulation of keratinocyte apoptotic process IEA
 biological_processGO:2000051 negative regulation of non-canonical Wnt signaling pathway IEA
 biological_processGO:2000119 negative regulation of sodium-dependent phosphate transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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