ENSGALG00000030847


Gallus gallus

Features
Gene ID: ENSGALG00000030847
  
Biological name :FZD2
  
Synonyms : frizzled-2 precursor / FZD2
  
Possible biological names infered from orthology : Frizzled-2 / frizzled class receptor 2 / Q14332 / Q9JIP6
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 1672021
Gene end: 1673804
  
Corresponding Affymetrix probe sets: Gga.312.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051122
NCBI entrez gene - 374061     See in Manteia.
RefSeq - NM_204222
RefSeq Peptide - NP_989553
swissprot - A0A1D5PEC1
Ensembl - ENSGALG00000030847
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fzd2ENSDARG00000054438Danio rerio
 FZD2ENSG00000180340Homo sapiens
 Fzd2ENSMUSG00000050288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497376
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906476
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410148
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999945
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200345
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192743
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265243
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724242
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230841
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062637
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611424
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347314
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199714
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276314
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751513
crescent precursor ENSGALG0000000694412
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG0000000924112
ENSGALG0000000863511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain
 IPR026550  Frizzled-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003149 membranous septum morphogenesis IEA
 biological_processGO:0003150 muscular septum morphogenesis IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007608 sensory perception of smell IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030825 obsolete positive regulation of cGMP metabolic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0060022 hard palate development IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060119 inner ear receptor cell development IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0090103 cochlea morphogenesis IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ pathway
Asymmetric localization of PCP proteins
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD2, FZD5 and ROR2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr