ENSGALG00000009241


Gallus gallus

Features
Gene ID: ENSGALG00000009241
  
Biological name :SFRP2
  
Synonyms : secreted frizzled-related protein 2 precursor / SFRP2
  
Possible biological names infered from orthology : P97299 / Q96HF1 / secreted frizzled related protein 2
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 20227180
Gene end: 20230889
  
Corresponding Affymetrix probe sets: Gga.4345.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015022
NCBI entrez gene - 395546     See in Manteia.
RefSeq - NM_204773
RefSeq Peptide - NP_990104
swissprot - F1P5J1
Ensembl - ENSGALG00000009241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sfrp2ENSDARG00000070050Danio rerio
 SFRP2ENSG00000145423Homo sapiens
 Sfrp2ENSMUSG00000027996Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347338
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751537
crescent precursor ENSGALG0000000694434
ENSGALG0000000863530
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192727
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200325
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906424
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410124
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999924
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497323
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724223
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084722
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265221
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230821
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062620
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276316
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199715
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR018933  Netrin module, non-TIMP type
 IPR020067  Frizzled domain
 IPR026558  Secreted frizzled-related protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0002063 chondrocyte development IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0003214 cardiac left ventricle morphogenesis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010950 positive regulation of endopeptidase activity IEA
 biological_processGO:0010975 regulation of neuron projection development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030199 collagen fibril organization IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0036342 post-anal tail morphogenesis IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042662 negative regulation of mesodermal cell fate specification IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043508 negative regulation of JUN kinase activity IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046546 development of primary male sexual characteristics IEA
 biological_processGO:0048546 digestive tract morphogenesis IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0060028 convergent extension involved in axis elongation IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0061056 sclerotome development IEA
 biological_processGO:0061185 negative regulation of dermatome development IEA
 biological_processGO:0071425 hematopoietic stem cell proliferation IEA
 biological_processGO:0071481 cellular response to X-ray IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090175 regulation of establishment of planar polarity IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IEA
 biological_processGO:0090244 Wnt signaling pathway involved in somitogenesis IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:1904956 regulation of midbrain dopaminergic neuron differentiation IEA
 biological_processGO:2000035 regulation of stem cell division IEA
 biological_processGO:2000041 negative regulation of planar cell polarity pathway involved in axis elongation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0048018 receptor ligand activity IEA
 molecular_functionGO:0061133 endopeptidase activator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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