ENSGALG00000002763


Gallus gallus

Features
Gene ID: ENSGALG00000002763
  
Biological name :FRZB
  
Synonyms : FRZB / secreted frizzled-related protein 3 precursor
  
Possible biological names infered from orthology : frizzled related protein / P97401 / Q92765 / Secreted frizzled-related protein 3
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 2312660
Gene end: 2328060
  
Corresponding Affymetrix probe sets: Gga.4955.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062378
Ensembl peptide - ENSGALP00000004354
NCBI entrez gene - 395545     See in Manteia.
RefSeq - NM_204772
RefSeq Peptide - NP_990103
swissprot - F1N884
swissprot - A0A1L1RU81
Ensembl - ENSGALG00000002763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frzbENSDARG00000018383Danio rerio
 FRZBENSG00000162998Homo sapiens
 FrzbENSMUSG00000027004Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199755
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999928
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410126
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497326
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906425
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084724
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724224
FZD6 / frizzled-6 precursor / Q61089* / O60353* / Frizzled-6 * / frizzled class receptor 6*ENSGALG0000003062623
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192723
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230822
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200322
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265219
crescent precursor ENSGALG0000000694417
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611417
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG0000000347317
ENSGALG0000000863516
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG0000000751516
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG0000000924115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR018933  Netrin module, non-TIMP type
 IPR020067  Frizzled domain
 IPR026556  Secreted frizzled-related protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010721 negative regulation of cell development IEA
 biological_processGO:0014033 neural crest cell differentiation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0060029 convergent extension involved in organogenesis IEA
 biological_processGO:0061037 negative regulation of cartilage development IEA
 biological_processGO:0061053 somite development IEA
 biological_processGO:0070367 negative regulation of hepatocyte differentiation IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090103 cochlea morphogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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