ENSGALG00000030626


Gallus gallus

Features
Gene ID: ENSGALG00000030626
  
Biological name :FZD6
  
Synonyms : frizzled-6 precursor / FZD6
  
Possible biological names infered from orthology : Frizzled-6 / frizzled class receptor 6 / O60353 / Q61089
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 129979749
Gene end: 130006976
  
Corresponding Affymetrix probe sets: Gga.2690.1.S1_at (Chicken Array)   Gga.2690.1.S1_a_at (Chicken Array)   Gga.2690.2.S1_a_at (Chicken Array)   Gga.3992.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053732
NCBI entrez gene - 378788     See in Manteia.
RefSeq - NM_001271931
RefSeq Peptide - NP_001258860
swissprot - A0A1D5PLL4
Ensembl - ENSGALG00000030626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01088508.1ENSDARG00000104874Danio rerio
 FZD6ENSG00000164930Homo sapiens
 Fzd6ENSMUSG00000022297Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FZD3 / frizzled class receptor 3 / Q61086* / Q9NPG1* / Frizzled-3 *ENSGALG0000004230849
FZD1 / frizzled-1 precursor / Q9UP38* / O70421* / Frizzled-1 * / frizzled class receptor 1*ENSGALG0000000906431
FZD7 / frizzled class receptor 7 / O75084* / Q61090* / Frizzled-7 *ENSGALG0000003497331
FZD2 / frizzled-2 precursor / Q9JIP6* / Q14332* / Frizzled-2 * / frizzled class receptor 2*ENSGALG0000003084729
FZD10 / frizzled-10 precursor / Q9ULW2* / Q8BKG4* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000004200328
FZD5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSGALG0000003410128
FZD8 / frizzled class receptor 8 / Q61091* / Q9H461* / Frizzled-8 *ENSGALG0000003999927
FZD9 / frizzled-9 precursor / Q9R216* / O00144* / Frizzled-9 * / frizzled class receptor 9*ENSGALG0000004192727
FZD10* / Q8BKG4* / Q9ULW2* / Frizzled-10 * / frizzled class receptor 10*ENSGALG0000000265226
FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*ENSGALG0000001724223
SMO / smoothened, frizzled class receptor / P56726* / Q99835*ENSGALG0000003611420
FRZB / secreted frizzled-related protein 3 precursor / P97401* / Q92765* / frizzled related protein* / Secreted frizzled-related protein 3 *ENSGALG0000000276310
SFRP4 / secreted frizzled related protein 4 / Q6FHJ7* / Q9Z1N6*ENSGALG0000003199710
SFRP1 / secreted frizzled related protein 1 / Q8C4U3* / Q8N474*ENSGALG000000034739
SFRP5 / Gallus gallus secreted frizzled related protein 5 (SFRP5), mRNA. / Q5T4F7* / secreted frizzled related protein 5* / secreted frizzled-related sequence protein 5*ENSGALG000000075158
crescent precursor ENSGALG000000069448
SFRP2 / secreted frizzled-related protein 2 precursor / P97299* / Q96HF1* / secreted frizzled related protein 2*ENSGALG000000092418
ENSGALG000000086358


Protein motifs (from Interpro)
Interpro ID Name
 IPR000539  Frizzled/Smoothened, transmembrane domain
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR017981  GPCR, family 2-like
 IPR020067  Frizzled domain
 IPR026543  Frizzled-6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001736 establishment of planar polarity IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0033278 cell proliferation in midbrain IEA
 biological_processGO:0035567 non-canonical Wnt signaling pathway IEA
 biological_processGO:0035880 embryonic nail plate morphogenesis IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0048105 establishment of body hair planar orientation IEA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016327 apicolateral plasma membrane IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0017147 Wnt-protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042813 Wnt-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ pathway
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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