Manteia

ENSDARG00000060004

Danio rerio

Features

Gene ID:	ENSDARG00000060004

Biological name :	fzd7a

Synonyms :	frizzled class receptor 7a / fzd7a

Possible biological names infered from orthology :	Frizzled-7 / frizzled class receptor 7 / FZD7 / O75084 / Q61090

Species:	Danio rerio

Chr. number:	9
Strand:	-1
Band:
Gene start:	13352308
Gene end:	13355071

Corresponding Affymetrix probe sets:	Dr.4823.1.S1_at (Zebrafish Array) NM_131139_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000106912 NCBI entrez gene - 30369 See in Manteia. RefSeq - NM_131139 RefSeq Peptide - NP_571214 swissprot - Q6NV44 ZFIN ID - ZDB-GENE-990415-223 Ensembl - ENSDARG00000060004

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
FZD7	ENSGALG00000034973	Gallus gallus
FZD7	ENSG00000155760	Homo sapiens
Fzd7	ENSMUSG00000041075	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
fzd7b / frizzled class receptor 7b / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*	ENSDARG00000027589	87
fzd1 / frizzled class receptor 1 / Q9UP38*	ENSDARG00000106062	74
fzd2 / frizzled class receptor 2 / Q14332* / Q9JIP6* / Frizzled-2 *	ENSDARG00000054438	71
fzd8a / frizzled class receptor 8a / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*	ENSDARG00000045444	48
fzd5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *	ENSDARG00000025420	47
fzd8b / frizzled class receptor 8b / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*	ENSDARG00000038569	46
fzd10 / frizzled class receptor 10 / Q8BKG4* / Q9ULW2* / Frizzled-10 *	ENSDARG00000068213	45
fzd9a / frizzled class receptor 9a / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*	ENSDARG00000035185	44
fzd9b / frizzled class receptor 9b / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*	ENSDARG00000014673	42
fzd3b / frizzled class receptor 3b	ENSDARG00000058692	41
fzd3a / frizzled class receptor 3a / FZD3* / Q61086* / Q9NPG1* / Frizzled-3 * / frizzled class receptor 3*	ENSDARG00000021664	40
CABZ01088508.1 / FZD6* / O60353* / frizzled class receptor 6*	ENSDARG00000104874	37
smo / smoothened, frizzled class receptor / P56726* / Q99835*	ENSDARG00000002952	23
sfrp5 / secreted frizzled-related protein 5 / Q5T4F7* / secreted frizzled-related sequence protein 5*	ENSDARG00000039041	14
sfrp1a / secreted frizzled-related protein 1a / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*	ENSDARG00000035521	14
sfrp1b / secreted frizzled-related protein 1b / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*	ENSDARG00000057678	14
frzb / frizzled related protein / P97401* / Q92765* / Secreted frizzled-related protein 3 *	ENSDARG00000018383	13
sfrp2 / secreted frizzled-related protein 2 / P97299* / Q96HF1*	ENSDARG00000070050	13
FP102169.1	ENSDARG00000110967	12
CZQB01095947.1	ENSDARG00000089563	12

Protein motifs (from Interpro)

Interpro ID	Name
IPR000539	Frizzled/Smoothened, transmembrane domain
IPR015526	Frizzled/secreted frizzled-related protein
IPR017981	GPCR, family 2-like
IPR020067	Frizzled domain
IPR026552	Frizzled-7

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007166	cell surface receptor signaling pathway	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0016055	Wnt signaling pathway	IEA
biological_process	GO:0035567	non-canonical Wnt signaling pathway	IBA
biological_process	GO:0042074	cell migration involved in gastrulation	IMP
biological_process	GO:0060027	convergent extension involved in gastrulation	IGI
biological_process	GO:0060070	canonical Wnt signaling pathway	IBA
biological_process	GO:0090504	epiboly	IGI
cellular_component	GO:0005886	plasma membrane	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IBA
molecular_function	GO:0017147	Wnt-protein binding	IBA
molecular_function	GO:0042813	Wnt-activated receptor activity	IEA

Pathways (from Reactome)

Pathway description

PCP/CE pathway

Asymmetric localization of PCP proteins

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000547	mouth	mouth decreased width , abnormal	Show
ZFA:0000737	cranium	cranium decreased size , abnormal	Show
ZFA:0001094	whole organism	whole organism decreased amount , abnormal	Show
ZFA:0001205	Meckel s cartilage	Meckels cartilage aplastic , abnormal	Show
ZFA:0001273	ventral mandibular arch	ventral mandibular arch absent , abnormal	Show
ZFA:0001321	neurocranial trabecula	neurocranial trabecula decreased size , abnormal neurocranial trabecula chondrocyte morphology , abnormal neurocranial trabecula chondrocyte circular , abnormal neurocranial trabecula chondrocyte disorganized , abnormal	Show
ZFA:0001405	ethmoid cartilage	ethmoid cartilage decreased size , abnormal ethmoid cartilage aplastic , abnormal	Show
ZFA:0001516	ceratobranchial cartilage	ceratobranchial cartilage absent , abnormal	Show
ZFA:0001612	pharyngeal arch 1	pharyngeal arch 1 mesenchyme decreased amount , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr