ENSDARG00000035521


Danio rerio

Features
Gene ID: ENSDARG00000035521
  
Biological name :sfrp1a
  
Synonyms : secreted frizzled-related protein 1a / sfrp1a
  
Possible biological names infered from orthology : Q8C4U3 / Q8N474 / secreted frizzled related protein 1 / SFRP1
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 27488975
Gene end: 27538745
  
Corresponding Affymetrix probe sets: Dr.25534.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000106722
Ensembl peptide - ENSDARP00000051490
NCBI entrez gene - 402843     See in Manteia.
RefSeq - NM_205585
RefSeq Peptide - NP_991148
swissprot - B0V369
swissprot - Q7T2K9
ZFIN ID - ZDB-GENE-040310-5
Ensembl - ENSDARG00000035521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SFRP1ENSGALG00000003473Gallus gallus
 SFRP1ENSG00000104332Homo sapiens
 Sfrp1ENSMUSG00000031548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sfrp1b / secreted frizzled-related protein 1b / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*ENSDARG0000005767862
sfrp5 / secreted frizzled-related protein 5 / Q5T4F7* / secreted frizzled-related sequence protein 5*ENSDARG0000003904157
sfrp2 / secreted frizzled-related protein 2 / P97299* / Q96HF1*ENSDARG0000007005038
FP102169.1ENSDARG0000011096734
CZQB01095947.1ENSDARG0000008956330
szl / sizzledENSDARG0000009963728
fzd7a / frizzled class receptor 7a / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000006000426
fzd1 / frizzled class receptor 1 / Q9UP38*ENSDARG0000010606225
fzd10 / frizzled class receptor 10 / Q8BKG4* / Q9ULW2* / Frizzled-10 *ENSDARG0000006821325
fzd7b / frizzled class receptor 7b / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*ENSDARG0000002758925
fzd8a / frizzled class receptor 8a / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000004544425
fzd5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *ENSDARG0000002542025
fzd8b / frizzled class receptor 8b / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*ENSDARG0000003856925
fzd2 / frizzled class receptor 2 / Q14332* / Q9JIP6* / Frizzled-2 *ENSDARG0000005443824
fzd9a / frizzled class receptor 9a / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000003518524
fzd3a / frizzled class receptor 3a / FZD3* / Q61086* / Q9NPG1* / Frizzled-3 * / frizzled class receptor 3*ENSDARG0000002166422
fzd9b / frizzled class receptor 9b / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*ENSDARG0000001467322
CABZ01088508.1 / FZD6* / O60353* / frizzled class receptor 6*ENSDARG0000010487421
fzd3b / frizzled class receptor 3bENSDARG0000005869221
smo / smoothened, frizzled class receptor / P56726* / Q99835*ENSDARG0000000295219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR015526  Frizzled/secreted frizzled-related protein
 IPR018933  Netrin module, non-TIMP type
 IPR020067  Frizzled domain
 IPR026559  Secreted frizzled-related protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IGI
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IGI
 biological_processGO:0030513 positive regulation of BMP signaling pathway IGI
 biological_processGO:0035567 non-canonical Wnt signaling pathway IBA
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IGI
 biological_processGO:0060070 canonical Wnt signaling pathway IBA
 biological_processGO:0061386 closure of optic fissure IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0042813 Wnt-activated receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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