Manteia

ENSDARG00000021664

Danio rerio

Features

Gene ID:	ENSDARG00000021664

Biological name :	fzd3a

Synonyms :	frizzled class receptor 3a / fzd3a

Possible biological names infered from orthology :	Frizzled-3 / frizzled class receptor 3 / FZD3 / Q61086 / Q9NPG1

Species:	Danio rerio

Chr. number:	20
Strand:	-1
Band:
Gene start:	35208855
Gene end:	35246150

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000084982 NCBI entrez gene - 565921 See in Manteia. RefSeq - XM_005160748 RefSeq Peptide - NP_001036226 swissprot - Q5TZ38 ZFIN ID - ZDB-GENE-990415-225 Ensembl - ENSDARG00000021664

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
FZD3	ENSGALG00000042308	Gallus gallus
FZD3	ENSG00000104290	Homo sapiens
Fzd3	ENSMUSG00000007989	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
fzd3b / frizzled class receptor 3b	ENSDARG00000058692	75
CABZ01088508.1 / FZD6* / O60353* / frizzled class receptor 6*	ENSDARG00000104874	42
fzd2 / frizzled class receptor 2 / Q14332* / Q9JIP6* / Frizzled-2 *	ENSDARG00000054438	33
fzd1 / frizzled class receptor 1 / Q9UP38*	ENSDARG00000106062	33
fzd7a / frizzled class receptor 7a / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*	ENSDARG00000060004	33
fzd7b / frizzled class receptor 7b / FZD7* / O75084* / Q61090* / Frizzled-7 * / frizzled class receptor 7*	ENSDARG00000027589	32
fzd5 / frizzled class receptor 5 / Q13467* / Q9EQD0* / Frizzled-5 *	ENSDARG00000025420	30
fzd8a / frizzled class receptor 8a / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*	ENSDARG00000045444	29
fzd9a / frizzled class receptor 9a / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*	ENSDARG00000035185	28
fzd9b / frizzled class receptor 9b / FZD9* / O00144* / Q9R216* / Frizzled-9 * / frizzled class receptor 9*	ENSDARG00000014673	28
fzd10 / frizzled class receptor 10 / Q8BKG4* / Q9ULW2* / Frizzled-10 *	ENSDARG00000068213	28
fzd8b / frizzled class receptor 8b / FZD8* / Q61091* / Q9H461* / Frizzled-8 * / frizzled class receptor 8*	ENSDARG00000038569	28
smo / smoothened, frizzled class receptor / P56726* / Q99835*	ENSDARG00000002952	21
sfrp2 / secreted frizzled-related protein 2 / P97299* / Q96HF1*	ENSDARG00000070050	10
frzb / frizzled related protein / P97401* / Q92765* / Secreted frizzled-related protein 3 *	ENSDARG00000018383	10
FP102169.1	ENSDARG00000110967	9
sfrp1a / secreted frizzled-related protein 1a / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*	ENSDARG00000035521	9
sfrp5 / secreted frizzled-related protein 5 / Q5T4F7* / secreted frizzled-related sequence protein 5*	ENSDARG00000039041	9
sfrp1b / secreted frizzled-related protein 1b / SFRP1* / Q8C4U3* / Q8N474* / secreted frizzled related protein 1*	ENSDARG00000057678	9
CZQB01095947.1	ENSDARG00000089563	8

Protein motifs (from Interpro)

Interpro ID	Name
IPR000539	Frizzled/Smoothened, transmembrane domain
IPR015526	Frizzled/secreted frizzled-related protein
IPR017981	GPCR, family 2-like
IPR020067	Frizzled domain
IPR026553	Frizzled-3, vertebrates

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007166	cell surface receptor signaling pathway	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0016055	Wnt signaling pathway	IEA
biological_process	GO:0021754	facial nucleus development	IMP
biological_process	GO:0033564	anterior/posterior axon guidance	IMP
biological_process	GO:0035567	non-canonical Wnt signaling pathway	IBA
biological_process	GO:0060070	canonical Wnt signaling pathway	IBA
biological_process	GO:0071679	commissural neuron axon guidance	IMP
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IBA
molecular_function	GO:0017147	Wnt-protein binding	IBA
molecular_function	GO:0042813	Wnt-activated receptor activity	IEA

Pathways (from Reactome)

Pathway description

Ca2+ pathway

PCP/CE pathway

Asymmetric localization of PCP proteins

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000206	facial nerve motor nucleus	facial nerve motor nucleus mislocalised , abnormal	Show
ZFA:0001094	whole organism	whole organism necrotic , abnormal whole organism anterior-posterior axis shortened , abnormal	Show
ZFA:0005175	CoPA	CoPA axon misrouted , abnormal CoPA axon mislocalised posteriorly , abnormal CoPA anterior/posterior axon guidance process quality , abnormal CoPA anterior/posterior axon guidance decreased process quality , abnormal CoPA dorsal spinal cord interneuron anterior axon guidance decreased process quality , abnormal CoPA neuron projection misrouted , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr