ENSG00000004777


Homo sapiens

Features
Gene ID: ENSG00000004777
  
Biological name :ARHGAP33
  
Synonyms : ARHGAP33 / O14559 / Rho GTPase activating protein 33
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35774532
Gene end: 35788822
  
Corresponding Affymetrix probe sets: 213827_at (Human Genome U133 Plus 2.0 Array)   215256_x_at (Human Genome U133 Plus 2.0 Array)   233885_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466443
Ensembl peptide - ENSP00000465411
Ensembl peptide - ENSP00000467844
Ensembl peptide - ENSP00000007510
Ensembl peptide - ENSP00000320038
Ensembl peptide - ENSP00000368227
NCBI entrez gene - 115703     See in Manteia.
OMIM - 614902
RefSeq - XM_017026238
RefSeq - XM_006722999
RefSeq - XM_011526416
RefSeq - XM_011526417
RefSeq - XM_011526418
RefSeq - XM_011526419
RefSeq - XM_011526420
RefSeq - XM_011526421
RefSeq - NM_001172630
RefSeq - NM_052948
RefSeq - XM_005258488
RefSeq Peptide - NP_001166101
RefSeq Peptide - NP_443180
swissprot - K7EQI6
swissprot - K7EK14
swissprot - A0A0A0MQQ9
swissprot - O14559
swissprot - K7EMC2
Ensembl - ENSG00000004777
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap33ENSDARG00000011333Danio rerio
 Q80YF9ENSMUSG00000036882Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A7KAX9 / ARHGAP32 / Rho GTPase activating protein 32ENSG0000013490946
Q2M1Z3 / ARHGAP31 / Rho GTPase activating protein 31ENSG0000003108122
Q7Z6I6 / ARHGAP30 / Rho GTPase activating protein 30ENSG0000018651721
Q52LW3 / ARHGAP29 / Rho GTPase activating protein 29ENSG0000013796212
GMIP / Q9P107 / GEM interacting proteinENSG0000008963912
Q92619 / ARHGAP45 / Rho GTPase activating protein 45ENSG0000018044811
A6NI28 / Q9H2Q1 / ARHGAP42 / Rho GTPase activating protein 42ENSG0000016589510
A1A4S6 / ARHGAP10 / Rho GTPase activating protein 10ENSG000000712059
Q15311 / RALBP1 / ralA binding protein 1ENSG000000177979
Q9UNA1 / ARHGAP26 / Rho GTPase activating protein 26ENSG000001458199
Q9H0H5 / RACGAP1 / Rac GTPase activating protein 1ENSG000001618008
OPHN1 / O60890 / oligophrenin 1ENSG000000794828


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR035510  Rho GTPase-activating protein 33
 IPR036028  SH3-like domain superfamily
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IBA
 cellular_componentGO:0015629 actin cytoskeleton IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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