ENSG00000089639


Homo sapiens

Features
Gene ID: ENSG00000089639
  
Biological name :GMIP
  
Synonyms : GEM interacting protein / GMIP / Q9P107
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 19629476
Gene end: 19643667
  
Corresponding Affymetrix probe sets: 218913_s_at (Human Genome U133 Plus 2.0 Array)   222782_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467946
Ensembl peptide - ENSP00000467054
Ensembl peptide - ENSP00000468662
Ensembl peptide - ENSP00000203556
Ensembl peptide - ENSP00000465108
Ensembl peptide - ENSP00000466045
NCBI entrez gene - 51291     See in Manteia.
OMIM - 609694
RefSeq - XM_017026862
RefSeq - NM_001288998
RefSeq - NM_001288999
RefSeq - NM_016573
RefSeq - XM_005259927
RefSeq - XM_011528048
RefSeq - XM_017026861
RefSeq Peptide - NP_057657
RefSeq Peptide - NP_001275928
RefSeq Peptide - NP_001275927
swissprot - K7EQR5
swissprot - Q9P107
swissprot - A0A024R7N1
swissprot - K7EJC2
swissprot - K7ELE8
Ensembl - ENSG00000089639
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmipENSDARG00000077249Danio rerio
 GmipENSMUSG00000036246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q52LW3 / ARHGAP29 / Rho GTPase activating protein 29ENSG0000013796233
Q92619 / ARHGAP45 / Rho GTPase activating protein 45ENSG0000018044832
A7KAX9 / ARHGAP32 / Rho GTPase activating protein 32ENSG0000013490915
O14559 / ARHGAP33 / Rho GTPase activating protein 33ENSG0000000477714
A1A4S6 / ARHGAP10 / Rho GTPase activating protein 10ENSG0000007120513
A6NI28 / Q9H2Q1 / ARHGAP42 / Rho GTPase activating protein 42ENSG0000016589513
Q9H0H5 / RACGAP1 / Rac GTPase activating protein 1ENSG0000016180012
OPHN1 / O60890 / oligophrenin 1ENSG0000007948212
Q9UNA1 / ARHGAP26 / Rho GTPase activating protein 26ENSG0000014581912
Q15311 / RALBP1 / ralA binding protein 1ENSG0000001779710
Q7Z6I6 / ARHGAP30 / Rho GTPase activating protein 30ENSG0000018651710
Q2M1Z3 / ARHGAP31 / Rho GTPase activating protein 31ENSG000000310819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0034260 negative regulation of GTPase activity IDA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0005096 GTPase activator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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