ENSG00000134909


Homo sapiens

Features
Gene ID: ENSG00000134909
  
Biological name :ARHGAP32
  
Synonyms : A7KAX9 / ARHGAP32 / Rho GTPase activating protein 32
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q24.3
Gene start: 128965060
Gene end: 129279324
  
Corresponding Affymetrix probe sets: 203431_s_at (Human Genome U133 Plus 2.0 Array)   210791_s_at (Human Genome U133 Plus 2.0 Array)   229648_at (Human Genome U133 Plus 2.0 Array)   242196_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432862
Ensembl peptide - ENSP00000376425
Ensembl peptide - ENSP00000432303
Ensembl peptide - ENSP00000432468
Ensembl peptide - ENSP00000310561
NCBI entrez gene - 9743     See in Manteia.
OMIM - 608541
RefSeq - XM_017018597
RefSeq - XM_011543072
RefSeq - XM_011543073
RefSeq - XM_011543075
RefSeq - XM_017018595
RefSeq - XM_017018596
RefSeq - NM_001142685
RefSeq - NM_014715
RefSeq - XM_005271736
RefSeq Peptide - NP_055530
RefSeq Peptide - NP_001136157
swissprot - E9PRH3
swissprot - G3V174
swissprot - A7KAX9
Ensembl - ENSG00000134909
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap32aENSDARG00000075334Danio rerio
 arhgap32bENSDARG00000074184Danio rerio
 ARHGAP32ENSGALG00000043511Gallus gallus
 Q811P8ENSMUSG00000041444Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O14559 / ARHGAP33 / Rho GTPase activating protein 33ENSG0000000477725
Q2M1Z3 / ARHGAP31 / Rho GTPase activating protein 31ENSG0000003108118
Q7Z6I6 / ARHGAP30 / Rho GTPase activating protein 30ENSG0000018651717
Q52LW3 / ARHGAP29 / Rho GTPase activating protein 29ENSG000001379628
GMIP / Q9P107 / GEM interacting proteinENSG000000896397
Q92619 / ARHGAP45 / Rho GTPase activating protein 45ENSG000001804487
Q15311 / RALBP1 / ralA binding protein 1ENSG000000177976
OPHN1 / O60890 / oligophrenin 1ENSG000000794826
A1A4S6 / ARHGAP10 / Rho GTPase activating protein 10ENSG000000712056
A6NI28 / Q9H2Q1 / ARHGAP42 / Rho GTPase activating protein 42ENSG000001658956
Q9UNA1 / ARHGAP26 / Rho GTPase activating protein 26ENSG000001458196
Q9H0H5 / RACGAP1 / Rac GTPase activating protein 1ENSG000001618005


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001452  SH3 domain
 IPR001683  Phox homologous domain
 IPR008936  Rho GTPase activation protein
 IPR036028  SH3-like domain superfamily
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IBA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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