ENSG00000092531


Homo sapiens

Features
Gene ID: ENSG00000092531
  
Biological name :SNAP23
  
Synonyms : O00161 / SNAP23 / synaptosome associated protein 23
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q15.1
Gene start: 42491233
Gene end: 42545356
  
Corresponding Affymetrix probe sets: 209130_at (Human Genome U133 Plus 2.0 Array)   209131_s_at (Human Genome U133 Plus 2.0 Array)   214544_s_at (Human Genome U133 Plus 2.0 Array)   229773_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457535
Ensembl peptide - ENSP00000458012
Ensembl peptide - ENSP00000486335
Ensembl peptide - ENSP00000485888
Ensembl peptide - ENSP00000207062
Ensembl peptide - ENSP00000249647
Ensembl peptide - ENSP00000380327
Ensembl peptide - ENSP00000454214
Ensembl peptide - ENSP00000454799
Ensembl peptide - ENSP00000454842
Ensembl peptide - ENSP00000455102
Ensembl peptide - ENSP00000455339
Ensembl peptide - ENSP00000455472
Ensembl peptide - ENSP00000455652
Ensembl peptide - ENSP00000456000
Ensembl peptide - ENSP00000456035
Ensembl peptide - ENSP00000456144
NCBI entrez gene - 8773     See in Manteia.
OMIM - 602534
RefSeq - XM_017022694
RefSeq - XM_017022693
RefSeq - NM_130798
RefSeq - NM_003825
RefSeq - XM_006720725
RefSeq - XM_017022692
RefSeq Peptide - NP_003816
RefSeq Peptide - NP_570710
swissprot - H3BR18
swissprot - H3BR99
swissprot - A8K287
swissprot - H3BV99
swissprot - O00161
swissprot - H3BU94
swissprot - A0A024R9R8
swissprot - H3BM38
swissprot - H3BNE1
swissprot - H3BNG6
swissprot - H3BP15
swissprot - H3BPJ0
swissprot - H3BQY9
Ensembl - ENSG00000092531
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snap23.1ENSDARG00000012874Danio rerio
 snap23.2ENSDARG00000055252Danio rerio
 SNAP23ENSGALG00000009097Gallus gallus
 O09044ENSMUSG00000027287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P60880 / SNAP25 / synaptosome associated protein 25ENSG0000013263955


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR000928  SNAP-25


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0002553 histamine secretion by mast cell IMP
 biological_processGO:0006892 post-Golgi vesicle-mediated transport TAS
 biological_processGO:0006903 vesicle targeting TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016082 synaptic vesicle priming IBA
 biological_processGO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0061025 membrane fusion TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0031201 SNARE complex IDA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0042581 specific granule IDA
 cellular_componentGO:0042582 azurophil granule IDA
 cellular_componentGO:0042629 mast cell granule IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IPI


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Clathrin derived vesicle budding
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / complex
 ENSG00000124333 VAMP7 / P51809 / vesicle associated membrane protein 7  / complex / reaction
 ENSG00000103496 STX4 / Q12846 / syntaxin 4  / reaction / complex
 ENSG00000220205 VAMP2 / P63027 / vesicle associated membrane protein 2  / complex / reaction
 ENSG00000118640 VAMP8 / Q9BV40 / vesicle associated membrane protein 8  / reaction / complex
 ENSG00000104365 IKBKB / O14920 / inhibitor of nuclear factor kappa B kinase subunit beta  / reaction






 

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