ENSG00000100867


Homo sapiens

Features
Gene ID: ENSG00000100867
  
Biological name :DHRS2
  
Synonyms : dehydrogenase/reductase 2 / DHRS2 / Q13268
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 23630115
Gene end: 23645639
  
Corresponding Affymetrix probe sets: 206463_s_at (Human Genome U133 Plus 2.0 Array)   214079_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451895
Ensembl peptide - ENSP00000451485
Ensembl peptide - ENSP00000481607
Ensembl peptide - ENSP00000250383
Ensembl peptide - ENSP00000344674
Ensembl peptide - ENSP00000401213
NCBI entrez gene - 10202     See in Manteia.
OMIM - 615194
RefSeq - XM_011536339
RefSeq - NM_005794
RefSeq - NM_182908
RefSeq - XM_005267249
RefSeq - XM_006720001
RefSeq - XM_011536338
RefSeq Peptide - NP_878912
RefSeq Peptide - NP_005785
swissprot - H0YJG9
swissprot - H0YJP4
swissprot - Q13268
swissprot - C9JZP6
Ensembl - ENSG00000100867
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhrs4ENSDARG00000021135Danio rerio
 Dhrs2ENSMUSG00000022209Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHRS4 / Q9BTZ2 / dehydrogenase/reductase 4ENSG0000015732649
Q6PKH6 / DHRS4L2 / dehydrogenase/reductase 4 like 2ENSG0000018763043
Q9BPX1 / HSD17B14 / hydroxysteroid 17-beta dehydrogenase 14ENSG0000008707623
CBR4 / Q8N4T8 / carbonyl reductase 4ENSG0000014543923
Q92506 / HSD17B8 / hydroxysteroid 17-beta dehydrogenase 8ENSG0000020422822
HPGD / P15428 / 15-hydroxyprostaglandin dehydrogenaseENSG0000016412021
Q99714 / HSD17B10 / hydroxysteroid 17-beta dehydrogenase 10ENSG0000007250621
BDH2 / Q9BUT1 / 3-hydroxybutyrate dehydrogenase 2ENSG0000016403921
DCXR / Q7Z4W1 / dicarbonyl and L-xylulose reductaseENSG0000016973821


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR027052  Dehydrogenase/reductase SDR member 2
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008207 C21-steroid hormone metabolic process NAS
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0034599 cellular response to oxidative stress IDA
 biological_processGO:0043011 myeloid dendritic cell differentiation IEP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004090 carbonyl reductase (NADPH) activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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