ENSG00000164039


Homo sapiens

Features
Gene ID: ENSG00000164039
  
Biological name :BDH2
  
Synonyms : 3-hydroxybutyrate dehydrogenase 2 / BDH2 / Q9BUT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q24
Gene start: 103079435
Gene end: 103099883
  
Corresponding Affymetrix probe sets: 218285_s_at (Human Genome U133 Plus 2.0 Array)   235155_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296424
Ensembl peptide - ENSP00000427442
Ensembl peptide - ENSP00000424173
Ensembl peptide - ENSP00000422891
Ensembl peptide - ENSP00000421516
NCBI entrez gene - 56898     See in Manteia.
RefSeq - NM_020139
RefSeq - XM_006714274
RefSeq - XM_011532127
RefSeq - XM_011532128
RefSeq - XM_017008461
RefSeq - XM_017008462
RefSeq - XM_005263140
RefSeq Peptide - NP_064524
swissprot - Q9BUT1
swissprot - D6RFG2
swissprot - D6RBF6
swissprot - D6R9U8
swissprot - A0A024RDG9
swissprot - D6RIR6
Ensembl - ENSG00000164039
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bdh2ENSDARG00000052696Danio rerio
 BDH2ENSGALG00000012338Gallus gallus
 Bdh2ENSMUSG00000028167Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HPGD / P15428 / 15-hydroxyprostaglandin dehydrogenaseENSG0000016412030
Q9BPX1 / HSD17B14 / hydroxysteroid 17-beta dehydrogenase 14ENSG0000008707630
Q92506 / HSD17B8 / hydroxysteroid 17-beta dehydrogenase 8ENSG0000020422829
DHRS4 / Q9BTZ2 / dehydrogenase/reductase 4ENSG0000015732627
Q99714 / HSD17B10 / hydroxysteroid 17-beta dehydrogenase 10ENSG0000007250626
CBR4 / Q8N4T8 / carbonyl reductase 4ENSG0000014543925
DHRS2 / Q13268 / dehydrogenase/reductase 2ENSG0000010086725
DCXR / Q7Z4W1 / dicarbonyl and L-xylulose reductaseENSG0000016973824
Q6PKH6 / DHRS4L2 / dehydrogenase/reductase 4 like 2ENSG0000018763022


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR003560  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006635 fatty acid beta-oxidation IDA
 biological_processGO:0019290 siderophore biosynthetic process IEA
 biological_processGO:0030855 epithelial cell differentiation IDA
 biological_processGO:0042168 heme metabolic process ISS
 biological_processGO:0046951 ketone body biosynthetic process TAS
 biological_processGO:0055072 iron ion homeostasis ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003858 3-hydroxybutyrate dehydrogenase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008667 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor ISS
 molecular_functionGO:0051287 NAD binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164039 BDH2 / Q9BUT1 / 3-hydroxybutyrate dehydrogenase 2  / complex






 

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