Manteia

ENSMUSG00000028167

Mus musculus

Features

Gene ID:	ENSMUSG00000028167

Biological name :	Bdh2

Synonyms :	3-hydroxybutyrate dehydrogenase type 2 / Bdh2 / Q8JZV9

Possible biological names infered from orthology :	3-hydroxybutyrate dehydrogenase 2 / Q9BUT1

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	G3
Gene start:	135281221
Gene end:	135304426

Corresponding Affymetrix probe sets:	10496251 (MoGene1.0st) 1453011_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000029817 Ensembl peptide - ENSMUSP00000112683 NCBI entrez gene - 69772 See in Manteia. MGI - MGI:1917022 RefSeq - NM_001172055 RefSeq - NM_027208 RefSeq Peptide - NP_001165526 RefSeq Peptide - NP_081484 swissprot - Q8JZV9 swissprot - G3UWD3 Ensembl - ENSMUSG00000028167

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Hsd17b14 / hydroxysteroid 17-beta dehydrogenase 14 / Q9BPX1*	ENSMUSG00000030825	31
Dhrs2 / dehydrogenase/reductase 2 / Q13268*	ENSMUSG00000022209	29
Hpgd / Q8VCC1 / 15-hydroxyprostaglandin dehydrogenase [NAD(+)] / P15428* / 15-hydroxyprostaglandin dehydrogenase*	ENSMUSG00000031613	28
P50171 / H2-Ke6 / H2-K region expressed gene 6 / Q92506* / HSD17B8* / hydroxysteroid 17-beta dehydrogenase 8*	ENSMUSG00000073422	28
Dcxr / Q91X52 / L-xylulose reductase / Q7Z4W1* / dicarbonyl and L-xylulose reductase*	ENSMUSG00000039450	27
Dhrs4 / Q99LB2 / Dehydrogenase/reductase SDR family member 4 / Q6PKH6* / Q9BTZ2* / DHRS4L2* / dehydrogenase/reductase 4* / dehydrogenase/reductase 4 like 2*	ENSMUSG00000022210	27
Hsd17b10 / hydroxysteroid 17-beta dehydrogenase 10 / Q99714*	ENSMUSG00000025260	26
Cbr2 / P08074 / Carbonyl reductase [NADPH] 2	ENSMUSG00000025150	26
Cbr4 / Q91VT4 / Carbonyl reductase family member 4 / Q8N4T8* / carbonyl reductase 4*	ENSMUSG00000031641	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR002347	Short-chain dehydrogenase/reductase SDR
IPR020904	Short-chain dehydrogenase/reductase, conserved site
IPR036291	NAD(P)-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006635	fatty acid beta-oxidation	ISS
biological_process	GO:0019290	siderophore biosynthetic process	IMP
biological_process	GO:0030855	epithelial cell differentiation	ISO
biological_process	GO:0042168	heme metabolic process	ISS
biological_process	GO:0055072	iron ion homeostasis	IMP
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005737	cytoplasm	ISS
cellular_component	GO:0005829	cytosol	ISO
molecular_function	GO:0003858	3-hydroxybutyrate dehydrogenase activity	ISS
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IMP
molecular_function	GO:0051287	NAD binding	ISS

Pathways (from Reactome)

Pathway description

Synthesis of Ketone Bodies

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0005561	increased mean corpuscular hemoglobin	"greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Asxl1^{tm1a(EUCOMM)Wtsi}/Asxl1⁺ Genetic Background: B6Dnk;B6Brd;B6N-Asxl1^{tm1a(EUCOMM)Wtsi} Tyr^c-Brd/WtsiH

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000028167	Bdh2 / Q8JZV9 / 3-hydroxybutyrate dehydrogenase type 2 / Q9BUT1* / 3-hydroxybutyrate dehydrogenase 2*	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr