ENSMUSG00000039450


Mus musculus

Features
Gene ID: ENSMUSG00000039450
  
Biological name :Dcxr
  
Synonyms : Dcxr / L-xylulose reductase / Q91X52
  
Possible biological names infered from orthology : dicarbonyl and L-xylulose reductase / Q7Z4W1
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 120725399
Gene end: 120727281
  
Corresponding Affymetrix probe sets: 10393926 (MoGene1.0st)   1419456_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026144
Ensembl peptide - ENSMUSP00000101754
NCBI entrez gene - 67880     See in Manteia.
MGI - MGI:1915130
RefSeq - XM_006534029
RefSeq - NM_026428
RefSeq - XM_006534027
RefSeq Peptide - NP_080704
RefSeq Peptide - NP_001334537
swissprot - Q91X52
swissprot - A2AC16
Ensembl - ENSMUSG00000039450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcxrENSDARG00000079271Danio rerio
 DCXRENSGALG00000002849Gallus gallus
 DCXRENSG00000169738Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cbr2 / P08074 / Carbonyl reductase [NADPH] 2 ENSMUSG0000002515065
P50171 / H2-Ke6 / H2-K region expressed gene 6 / Q92506* / HSD17B8* / hydroxysteroid 17-beta dehydrogenase 8*ENSMUSG0000007342232
Dhrs4 / Q99LB2 / Dehydrogenase/reductase SDR family member 4 / Q6PKH6* / Q9BTZ2* / DHRS4L2* / dehydrogenase/reductase 4* / dehydrogenase/reductase 4 like 2*ENSMUSG0000002221028
Dhrs2 / dehydrogenase/reductase 2 / Q13268*ENSMUSG0000002220928
Cbr4 / Q91VT4 / Carbonyl reductase family member 4 / Q8N4T8* / carbonyl reductase 4*ENSMUSG0000003164128
Bdh2 / Q8JZV9 / 3-hydroxybutyrate dehydrogenase type 2 / Q9BUT1* / 3-hydroxybutyrate dehydrogenase 2*ENSMUSG0000002816728
Hsd17b14 / hydroxysteroid 17-beta dehydrogenase 14 / Q9BPX1*ENSMUSG0000003082526
Hpgd / Q8VCC1 / 15-hydroxyprostaglandin dehydrogenase [NAD(+)] / P15428* / 15-hydroxyprostaglandin dehydrogenase*ENSMUSG0000003161323
Hsd17b10 / hydroxysteroid 17-beta dehydrogenase 10 / Q99714*ENSMUSG0000002526023


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005997 xylulose metabolic process IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006739 NADP metabolic process IDA
 biological_processGO:0042732 D-xylose metabolic process IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005881 cytoplasmic microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0005903 brush border IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IDA
 molecular_functionGO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044105 L-xylulose reductase (NAD+) activity IEA
 molecular_functionGO:0050038 L-xylulose reductase (NADP+) activity ISO


Pathways (from Reactome)
Pathway description
Formation of xylulose-5-phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039450 Dcxr / Q91X52 / L-xylulose reductase / Q7Z4W1* / dicarbonyl and L-xylulose reductase*  / complex






 

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