ENSMUSG00000031641


Mus musculus

Features
Gene ID: ENSMUSG00000031641
  
Biological name :Cbr4
  
Synonyms : Carbonyl reductase family member 4 / Cbr4 / Q91VT4
  
Possible biological names infered from orthology : carbonyl reductase 4 / Q8N4T8
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.1
Gene start: 61487734
Gene end: 61506694
  
Corresponding Affymetrix probe sets: 10571978 (MoGene1.0st)   1451398_at (Mouse Genome 430 2.0 Array)   1456799_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117069
Ensembl peptide - ENSMUSP00000034058
NCBI entrez gene - 234309     See in Manteia.
MGI - MGI:2384567
RefSeq - NM_145595
RefSeq Peptide - NP_663570
swissprot - D3Z6C4
swissprot - Q91VT4
Ensembl - ENSMUSG00000031641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbr4ENSDARG00000009074Danio rerio
 CBR4ENSGALG00000009714Gallus gallus
 CBR4ENSG00000145439Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P50171 / H2-Ke6 / H2-K region expressed gene 6 / Q92506* / HSD17B8* / hydroxysteroid 17-beta dehydrogenase 8*ENSMUSG0000007342236
Dhrs2 / dehydrogenase/reductase 2 / Q13268*ENSMUSG0000002220932
Hsd17b14 / hydroxysteroid 17-beta dehydrogenase 14 / Q9BPX1*ENSMUSG0000003082531
Dcxr / Q91X52 / L-xylulose reductase / Q7Z4W1* / dicarbonyl and L-xylulose reductase*ENSMUSG0000003945029
Dhrs4 / Q99LB2 / Dehydrogenase/reductase SDR family member 4 / Q6PKH6* / Q9BTZ2* / DHRS4L2* / dehydrogenase/reductase 4* / dehydrogenase/reductase 4 like 2*ENSMUSG0000002221029
Bdh2 / Q8JZV9 / 3-hydroxybutyrate dehydrogenase type 2 / Q9BUT1* / 3-hydroxybutyrate dehydrogenase 2*ENSMUSG0000002816728
Hpgd / Q8VCC1 / 15-hydroxyprostaglandin dehydrogenase [NAD(+)] / P15428* / 15-hydroxyprostaglandin dehydrogenase*ENSMUSG0000003161328
Hsd17b10 / hydroxysteroid 17-beta dehydrogenase 10 / Q99714*ENSMUSG0000002526027
Cbr2 / P08074 / Carbonyl reductase [NADPH] 2 ENSMUSG0000002515026


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process ISO
 biological_processGO:0044597 daunorubicin metabolic process IEA
 biological_processGO:0044598 doxorubicin metabolic process IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0051290 protein heterotetramerization IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix ISO
 cellular_componentGO:1990204 oxidoreductase complex IEA
 molecular_functionGO:0003955 NAD(P)H dehydrogenase (quinone) activity IEA
 molecular_functionGO:0008753 NADPH dehydrogenase (quinone) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity IEA
 molecular_functionGO:0048038 quinone binding IEA
 molecular_functionGO:0070402 NADPH binding IEA


Pathways (from Reactome)
Pathway description
Fatty acyl-CoA biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031641 Cbr4 / Q91VT4 / Carbonyl reductase family member 4 / Q8N4T8* / carbonyl reductase 4*  / complex
 ENSMUSG00000073422 P50171 / H2-Ke6 / H2-K region expressed gene 6 / Q92506* / HSD17B8* / hydroxysteroid 17-beta dehydrogenase 8*  / complex






 

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