ENSG00000104974


Homo sapiens

Features
Gene ID: ENSG00000104974
  
Biological name :LILRA1
  
Synonyms : leukocyte immunoglobulin like receptor A1 / LILRA1 / O75019
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 54593582
Gene end: 54602090
  
Corresponding Affymetrix probe sets: 207872_s_at (Human Genome U133 Plus 2.0 Array)   210660_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000251372
Ensembl peptide - ENSP00000413715
NCBI entrez gene - 11024     See in Manteia.
OMIM - 604810
RefSeq - NM_001278319
RefSeq - NM_001278318
RefSeq - NM_006863
RefSeq Peptide - NP_001265247
RefSeq Peptide - NP_001265248
RefSeq Peptide - NP_006854
swissprot - O75019
Ensembl - ENSG00000104974
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2ENSG0000023999878
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497277
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104276
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448266
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3ENSG0000020457763
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996162
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560958
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711632
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681828
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040327
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201926
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG0000016763326
NCR1 / O76036 / natural cytotoxicity triggering receptor 1ENSG0000018943023
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497022
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805322
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549819
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643119
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377219
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4ENSG0000018901318
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195714


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR016332  Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003823 antigen binding TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / reaction / complex






 

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