Manteia

ENSG00000186431

Homo sapiens

Features

Gene ID:	ENSG00000186431

Biological name :	FCAR

Synonyms :	FCAR / Fc fragment of IgA receptor / P24071

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	19
Strand:	1
Band:	q13.42
Gene start:	54874248
Gene end:	54890472

Corresponding Affymetrix probe sets:	207674_at (Human Genome U133 Plus 2.0 Array) 211305_x_at (Human Genome U133 Plus 2.0 Array) 211306_s_at (Human Genome U133 Plus 2.0 Array) 211307_s_at (Human Genome U133 Plus 2.0 Array) 211816_x_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000375605 Ensembl peptide - ENSP00000375604 Ensembl peptide - ENSP00000375606 Ensembl peptide - ENSP00000474512 Ensembl peptide - ENSP00000473814 Ensembl peptide - ENSP00000338058 Ensembl peptide - ENSP00000338257 Ensembl peptide - ENSP00000347714 Ensembl peptide - ENSP00000352218 Ensembl peptide - ENSP00000375603 NCBI entrez gene - 2204 See in Manteia. OMIM - 147045 RefSeq - XM_017026474 RefSeq - NM_002000 RefSeq - NM_133269 RefSeq - NM_133271 RefSeq - NM_133272 RefSeq - NM_133273 RefSeq - NM_133274 RefSeq - NM_133277 RefSeq - NM_133278 RefSeq - XM_011526625 RefSeq - XM_017026473 RefSeq Peptide - NP_001991 RefSeq Peptide - NP_579803 RefSeq Peptide - NP_579807 RefSeq Peptide - NP_579808 RefSeq Peptide - NP_579811 RefSeq Peptide - NP_579812 RefSeq Peptide - NP_579805 RefSeq Peptide - NP_579806 swissprot - A0A024R4R4 swissprot - A0A024R4N4 swissprot - P24071 swissprot - A0A024R4M5 Ensembl - ENSG00000186431

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name

Species

No match

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1	ENSG00000104974	33
LILRB1 / leukocyte immunoglobulin like receptor B1	ENSG00000104972	33
NCR1 / O76036 / natural cytotoxicity triggering receptor 1	ENSG00000189430	33
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2	ENSG00000239998	33
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6	ENSG00000244482	32
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4	ENSG00000239961	32
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2	ENSG00000131042	32
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5	ENSG00000187116	32
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3	ENSG00000204577	32
GP6 / Q9HCN6 / glycoprotein VI platelet	ENSG00000088053	31
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4	ENSG00000186818	31
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2	ENSG00000240403	29
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	ENSG00000167633	29
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5	ENSG00000105609	28
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3	ENSG00000242019	24
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1	ENSG00000104970	24
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	ENSG00000243772	19
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1	ENSG00000125498	18
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4	ENSG00000221957	15
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	ENSG00000189013	13

Protein motifs (from Interpro)

Interpro ID	Name
IPR003599	Immunoglobulin subtype
IPR013151	Immunoglobulin
IPR013783	Immunoglobulin-like fold
IPR036179	Immunoglobulin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006955	immune response	TAS
biological_process	GO:0043312	neutrophil degranulation	TAS
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005886	plasma membrane	TAS
cellular_component	GO:0005887	integral component of plasma membrane	TAS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0035579	specific granule membrane	TAS
cellular_component	GO:0070821	tertiary granule membrane	TAS
cellular_component	GO:0101003	ficolin-1-rich granule membrane	TAS
molecular_function	GO:0019862	IgA binding	IEA

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr