Manteia

ENSG00000243772

Homo sapiens

Features

Gene ID:	ENSG00000243772

Biological name :	KIR2DL3

Synonyms :	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 / KIR2DL3 / P43628

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	19
Strand:	1
Band:	q13.42
Gene start:	54738515
Gene end:	54753052

Corresponding Affymetrix probe sets:	208179_x_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000342215 NCBI entrez gene - 3804 See in Manteia. OMIM - 604938 RefSeq - NM_015868 RefSeq Peptide - NP_056952 swissprot - E3NZD8 swissprot - P43628 Ensembl - ENSG00000243772

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
Kir3dl1	ENSMUSG00000031424	Mus musculus
Kir3dl2	ENSMUSG00000057439	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1	ENSG00000125498	91
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2	ENSG00000240403	85
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	ENSG00000167633	84
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3	ENSG00000242019	74
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	ENSG00000189013	47
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4	ENSG00000221957	46
LILRB1 / leukocyte immunoglobulin like receptor B1	ENSG00000104972	37
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2	ENSG00000131042	36
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3	ENSG00000204577	34
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5	ENSG00000105609	33
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1	ENSG00000104970	32
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4	ENSG00000239961	29
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2	ENSG00000239998	29
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1	ENSG00000104974	28
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6	ENSG00000244482	28
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4	ENSG00000186818	21
GP6 / Q9HCN6 / glycoprotein VI platelet	ENSG00000088053	21
NCR1 / O76036 / natural cytotoxicity triggering receptor 1	ENSG00000189430	16
FCAR / P24071 / Fc fragment of IgA receptor	ENSG00000186431	16
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5	ENSG00000187116	16

Protein motifs (from Interpro)

Interpro ID	Name
IPR003599	Immunoglobulin subtype
IPR013151	Immunoglobulin
IPR013783	Immunoglobulin-like fold
IPR036179	Immunoglobulin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006955	immune response	TAS
biological_process	GO:0050776	regulation of immune response	TAS
cellular_component	GO:0005886	plasma membrane	TAS
cellular_component	GO:0005887	integral component of plasma membrane	TAS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	TAS
molecular_function	GO:0003823	antigen binding	TAS
molecular_function	GO:0005515	protein binding	IPI

Pathways (from Reactome)

Pathway description

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSG00000166710	B2M / P61769 / beta-2-microglobulin	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr