ENSG00000239998


Homo sapiens

Features
Gene ID: ENSG00000239998
  
Biological name :LILRA2
  
Synonyms : leukocyte immunoglobulin like receptor A2 / LILRA2 / Q8N149
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 54572920
Gene end: 54590287
  
Corresponding Affymetrix probe sets: 207857_at (Human Genome U133 Plus 2.0 Array)   211100_x_at (Human Genome U133 Plus 2.0 Array)   211101_x_at (Human Genome U133 Plus 2.0 Array)   211102_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375617
Ensembl peptide - ENSP00000251377
Ensembl peptide - ENSP00000375618
Ensembl peptide - ENSP00000486483
Ensembl peptide - ENSP00000477566
Ensembl peptide - ENSP00000388131
Ensembl peptide - ENSP00000251376
NCBI entrez gene - 11027     See in Manteia.
OMIM - 604812
RefSeq - XM_017026224
RefSeq - XM_011526385
RefSeq - XM_011526386
RefSeq - XM_011526387
RefSeq - XM_011526388
RefSeq - XM_011526390
RefSeq - XM_011526391
RefSeq - NM_001130917
RefSeq - NM_001290270
RefSeq - NM_001290271
RefSeq - NM_006866
RefSeq - XM_006722986
RefSeq Peptide - NP_001277200
swissprot - E9PDF4
swissprot - A8MZH0
swissprot - A0A0D9SFC7
swissprot - A0A087WT41
swissprot - Q8N149
Ensembl - ENSG00000239998
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1ENSG0000010497478
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497275
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104273
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448265
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3ENSG0000020457763
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996161
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560960
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711630
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681829
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG0000016763327
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040327
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201926
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497023
NCR1 / O76036 / natural cytotoxicity triggering receptor 1ENSG0000018943023
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805323
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549820
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643120
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377220
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4ENSG0000018901318
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195715


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR016332  Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002220 innate immune response activating cell surface receptor signaling pathway IDA
 biological_processGO:0002283 neutrophil activation involved in immune response IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0032604 granulocyte macrophage colony-stimulating factor production IMP
 biological_processGO:0032635 interleukin-6 production IMP
 biological_processGO:0032637 interleukin-8 production IMP
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0071611 granulocyte colony-stimulating factor production IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001791 IgM binding IDA
 molecular_functionGO:0003823 antigen binding TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr