ENSG00000204577


Homo sapiens

Features
Gene ID: ENSG00000204577
  
Biological name :LILRB3
  
Synonyms : leukocyte immunoglobulin like receptor B3 / LILRB3 / O75022
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 54216278
Gene end: 54223506
  
Corresponding Affymetrix probe sets: 210225_x_at (Human Genome U133 Plus 2.0 Array)   210784_x_at (Human Genome U133 Plus 2.0 Array)   211133_x_at (Human Genome U133 Plus 2.0 Array)   211135_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416920
Ensembl peptide - ENSP00000245620
Ensembl peptide - ENSP00000345184
Ensembl peptide - ENSP00000375630
Ensembl peptide - ENSP00000388199
NCBI entrez gene - 102725035     See in Manteia.
NCBI entrez gene - 107987425     See in Manteia.
NCBI entrez gene - 107987462     See in Manteia.
NCBI entrez gene - 11025     See in Manteia.
OMIM - 604820
RefSeq - XM_017026223
RefSeq - XM_011526381
RefSeq - XM_011526382
RefSeq - XM_017026218
RefSeq - XM_017026219
RefSeq - XM_017026220
RefSeq - XM_017026221
RefSeq - XM_017026222
RefSeq - NM_001081450
RefSeq - NM_001320960
RefSeq - NM_006864
RefSeq Peptide - NP_006855
RefSeq Peptide - NP_001074919
RefSeq Peptide - NP_001307889
swissprot - C9JWL8
swissprot - O75022
swissprot - F8WD89
swissprot - F8W6G6
Ensembl - ENSG00000204577
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Gm14548ENSMUSG00000074417Mus musculus
 Gm15448ENSMUSG00000074419Mus musculus
 Gm15922ENSMUSG00000081665Mus musculus
 Lilr4bENSMUSG00000112023Mus musculus
 Lilra5ENSMUSG00000070873Mus musculus
 Lilra6ENSMUSG00000030427Mus musculus
 Lilrb4ENSMUSG00000112148Mus musculus
 Pira2ENSMUSG00000089942Mus musculus
 PirbENSMUSG00000058818Mus musculus
 Q64281ENSMUSG00000062593Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497270
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448268
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104263
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560962
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996152
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1ENSG0000010497449
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2ENSG0000023999848
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681847
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711628
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040324
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201924
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG0000016763324
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805320
NCR1 / O76036 / natural cytotoxicity triggering receptor 1ENSG0000018943019
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377219
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549818
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4ENSG0000018901318
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497018
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643115
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195711


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045671 negative regulation of osteoclast differentiation IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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