ENSG00000167633


Homo sapiens

Features
Gene ID: ENSG00000167633
  
Biological name :KIR3DL1
  
Synonyms : killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 / KIR3DL1 / P43629
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 54816468
Gene end: 54830778
  
Corresponding Affymetrix probe sets: 211389_x_at (Human Genome U133 Plus 2.0 Array)   211687_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000326868
Ensembl peptide - ENSP00000350901
Ensembl peptide - ENSP00000375608
NCBI entrez gene - 3811     See in Manteia.
OMIM - 604946
RefSeq - NM_013289
RefSeq Peptide - NP_037421
swissprot - P43629
swissprot - Q5UCE2
swissprot - W5QJC1
Ensembl - ENSG00000167633
  
Related genetic diseases (OMIM): 609423 - {AIDS, delayed/rapid progression to}, 609423
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Kir3dl1ENSMUSG00000031424Mus musculus
 Kir3dl2ENSMUSG00000057439Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040386
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201970
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549866
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377265
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4ENSG0000018901351
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497236
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3ENSG0000020457734
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497034
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104234
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560933
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195732
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448230
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996129
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2ENSG0000023999829
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1ENSG0000010497429
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805323
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681822
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711620
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643119
NCR1 / O76036 / natural cytotoxicity triggering receptor 1ENSG0000018943019


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response NAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IMP
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030109 HLA-B specific inhibitory MHC class I receptor activity NAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / reaction / complex






 

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