ENSG00000189013


Homo sapiens

Features
Gene ID: ENSG00000189013
  
Biological name :KIR2DL4
  
Synonyms : killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 / KIR2DL4 / Q99706
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 54803535
Gene end: 54814517
  
Corresponding Affymetrix probe sets: 208426_x_at (Human Genome U133 Plus 2.0 Array)   211242_x_at (Human Genome U133 Plus 2.0 Array)   211245_x_at (Human Genome U133 Plus 2.0 Array)   211410_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350088
Ensembl peptide - ENSP00000379588
Ensembl peptide - ENSP00000379584
Ensembl peptide - ENSP00000379580
Ensembl peptide - ENSP00000351988
Ensembl peptide - ENSP00000339634
Ensembl peptide - ENSP00000345331
NCBI entrez gene - 3805     See in Manteia.
OMIM - 604945
RefSeq - NM_001080772
RefSeq - NM_001080770
RefSeq Peptide - NP_001074239
RefSeq Peptide - NP_001074241
swissprot - Q99706
swissprot - A8MT18
swissprot - A0A0B4J1S6
swissprot - Q8N736
swissprot - E7EST5
Ensembl - ENSG00000189013
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Kir3dl1ENSMUSG00000031424Mus musculus
 Kir3dl2ENSMUSG00000057439Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040368
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG0000016763367
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201961
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549847
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377246
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497234
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104232
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497032
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3ENSG0000020457732
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560930
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448228
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1ENSG0000010497426
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2ENSG0000023999825
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996125
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805318
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195718
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681817
NCR1 / O76036 / natural cytotoxicity triggering receptor 1ENSG0000018943014
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711613
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643111


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / complex / reaction
 ENSG00000204632 HLA-G / P17693 / major histocompatibility complex, class I, G  / reaction / complex






 

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