ENSG00000189430


Homo sapiens

Features
Gene ID: ENSG00000189430
  
Biological name :NCR1
  
Synonyms : natural cytotoxicity triggering receptor 1 / NCR1 / O76036
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 54906150
Gene end: 54916140
  
Corresponding Affymetrix probe sets: 207860_at (Human Genome U133 Plus 2.0 Array)   217088_s_at (Human Genome U133 Plus 2.0 Array)   217095_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000344358
Ensembl peptide - ENSP00000339515
Ensembl peptide - ENSP00000349972
Ensembl peptide - ENSP00000471986
Ensembl peptide - ENSP00000469750
Ensembl peptide - ENSP00000291890
NCBI entrez gene - 9437     See in Manteia.
OMIM - 604530
RefSeq - XM_011527530
RefSeq - NM_001145457
RefSeq - NM_001145458
RefSeq - NM_001242356
RefSeq - NM_001242357
RefSeq - NM_004829
RefSeq - XM_011527528
RefSeq - XM_011527529
RefSeq Peptide - NP_001229286
RefSeq Peptide - NP_001229285
swissprot - M0QYD1
swissprot - A0A0A0MTU0
swissprot - O76036
swissprot - A0A0A0MQZ0
swissprot - A0A0A0MR94
Ensembl - ENSG00000189430
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ncr1ENSMUSG00000062524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3ENSG0000020457740
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6ENSG0000024448239
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4ENSG0000023996139
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1ENSG0000010497437
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2ENSG0000023999837
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5ENSG0000010560937
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2ENSG0000013104236
LILRB4 / Q8NHJ6 / leukocyte immunoglobulin like receptor B4ENSG0000018681836
LILRB1 / leukocyte immunoglobulin like receptor B1ENSG0000010497236
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5ENSG0000018711634
FCAR / P24071 / Fc fragment of IgA receptorENSG0000018643131
GP6 / Q9HCN6 / glycoprotein VI plateletENSG0000008805329
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1ENSG0000016763327
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3ENSG0000024201927
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG0000024040327
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1ENSG0000010497024
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3ENSG0000024377218
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG0000012549817
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4ENSG0000018901316
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4ENSG0000022195713


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0030101 natural killer cell activation NAS
 biological_processGO:0042269 regulation of natural killer cell mediated cytotoxicity TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016514 SWI/SNF complex ISS
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000198821 CD247 / P20963 / CD247 molecule  / complex
 ENSG00000150337 FCGR1A / P12314 / Fc fragment of IgG receptor Ia  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr