ENSG00000105866


Homo sapiens

Features
Gene ID: ENSG00000105866
  
Biological name :SP4
  
Synonyms : Q02446 / SP4 / Sp4 transcription factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p15.3
Gene start: 21428034
Gene end: 21514822
  
Corresponding Affymetrix probe sets: 206663_at (Human Genome U133 Plus 2.0 Array)   236265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393623
Ensembl peptide - ENSP00000222584
Ensembl peptide - ENSP00000390817
NCBI entrez gene - 6671     See in Manteia.
OMIM - 600540
RefSeq - XM_011515486
RefSeq - NM_001326542
RefSeq - NM_001326543
RefSeq - NM_003112
RefSeq - XM_005249828
RefSeq - XM_005249829
RefSeq Peptide - NP_001313472
RefSeq Peptide - NP_003103
RefSeq Peptide - NP_001313471
swissprot - F8WB93
swissprot - Q02446
swissprot - C9JUS7
Ensembl - ENSG00000105866
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sp4ENSDARG00000005186Danio rerio
 SP4ENSGALG00000039454Gallus gallus
 Sp4ENSMUSG00000025323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SP1 / P08047 / Sp1 transcription factorENSG0000018559138
SP3 / Q02447 / Sp3 transcription factorENSG0000017284538
SP2 / Q02086 / Sp2 transcription factorENSG0000016718227
SP8 / Q8IXZ3 / Sp8 transcription factorENSG0000016465120
SP9 / P0CG40 / Sp9 transcription factorENSG0000021723618
SP5 / Q6BEB4 / Sp5 transcription factorENSG0000020433518
SP7 / Q8TDD2 / Sp7 transcription factorENSG0000017037417
KLF11 / O14901 / Kruppel like factor 11ENSG0000017205914
SP6 / Q3SY56 / Sp6 transcription factorENSG0000018912014
KLF10 / Q13118 / Kruppel like factor 10ENSG0000015509012
KLF14 / Kruppel like factor 14ENSG0000026626511
KLF13 / Q9Y2Y9 / Kruppel like factor 13ENSG0000016992610
KLF9 / Q13886 / Kruppel like factor 9ENSG0000011913810
KLF16 / Q9BXK1 / Kruppel like factor 16ENSG000001299119


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR030453  Transcription factor Sp4
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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