ENSG00000167182


Homo sapiens

Features
Gene ID: ENSG00000167182
  
Biological name :SP2
  
Synonyms : Q02086 / SP2 / Sp2 transcription factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.32
Gene start: 47896150
Gene end: 47928957
  
Corresponding Affymetrix probe sets: 204367_at (Human Genome U133 Plus 2.0 Array)   211736_at (Human Genome U133 Plus 2.0 Array)   237795_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484898
Ensembl peptide - ENSP00000365931
Ensembl peptide - ENSP00000489736
Ensembl peptide - ENSP00000493268
Ensembl peptide - ENSP00000490512
Ensembl peptide - ENSP00000490351
NCBI entrez gene - 6668     See in Manteia.
OMIM - 601801
RefSeq - XM_017024969
RefSeq - XM_006722026
RefSeq - XM_006722027
RefSeq - XM_011525139
RefSeq - XM_011525140
RefSeq - XM_011525142
RefSeq - XM_011525143
RefSeq - XM_017024968
RefSeq - NM_003110
RefSeq - XM_006722023
RefSeq - XM_006722025
RefSeq Peptide - NP_003101
swissprot - A0A1B0GVH1
swissprot - A0A1B0GV29
swissprot - A0A286YFJ7
swissprot - Q02086
swissprot - Q9BRW5
swissprot - A0A1B0GTK3
Ensembl - ENSG00000167182
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sp2ENSDARG00000076763Danio rerio
 SP2ENSGALG00000000233Gallus gallus
 Sp2ENSMUSG00000018678Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SP4 / Q02446 / Sp4 transcription factorENSG0000010586634
SP1 / P08047 / Sp1 transcription factorENSG0000018559133
SP3 / Q02447 / Sp3 transcription factorENSG0000017284532
SP9 / P0CG40 / Sp9 transcription factorENSG0000021723620
SP8 / Q8IXZ3 / Sp8 transcription factorENSG0000016465119
SP5 / Q6BEB4 / Sp5 transcription factorENSG0000020433519
SP7 / Q8TDD2 / Sp7 transcription factorENSG0000017037417
KLF11 / O14901 / Kruppel like factor 11ENSG0000017205917
KLF10 / Q13118 / Kruppel like factor 10ENSG0000015509016
SP6 / Q3SY56 / Sp6 transcription factorENSG0000018912015
KLF14 / Kruppel like factor 14ENSG0000026626512
KLF13 / Q9Y2Y9 / Kruppel like factor 13ENSG0000016992612
KLF16 / Q9BXK1 / Kruppel like factor 16ENSG0000012991112
KLF9 / Q13886 / Kruppel like factor 9ENSG0000011913811


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR030451  Transcription factor Sp2
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0035264 multicellular organism growth IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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