ENSG00000155090


Homo sapiens

Features
Gene ID: ENSG00000155090
  
Biological name :KLF10
  
Synonyms : KLF10 / Kruppel like factor 10 / Q13118
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q22.3
Gene start: 102648779
Gene end: 102655902
  
Corresponding Affymetrix probe sets: 202393_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000285407
Ensembl peptide - ENSP00000379222
NCBI entrez gene - 7071     See in Manteia.
OMIM - 601878
RefSeq - NM_001032282
RefSeq - NM_005655
RefSeq Peptide - NP_001027453
RefSeq Peptide - NP_005646
swissprot - Q13118
Ensembl - ENSG00000155090
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLF10ENSGALG00000037913Gallus gallus
 Klf10ENSMUSG00000037465Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF11 / O14901 / Kruppel like factor 11ENSG0000017205937
SP1 / P08047 / Sp1 transcription factorENSG0000018559121
SP2 / Q02086 / Sp2 transcription factorENSG0000016718220
SP3 / Q02447 / Sp3 transcription factorENSG0000017284519
KLF14 / Kruppel like factor 14ENSG0000026626519
SP4 / Q02446 / Sp4 transcription factorENSG0000010586619
SP8 / Q8IXZ3 / Sp8 transcription factorENSG0000016465118
KLF13 / Q9Y2Y9 / Kruppel like factor 13ENSG0000016992618
SP7 / Q8TDD2 / Sp7 transcription factorENSG0000017037417
KLF16 / Q9BXK1 / Kruppel like factor 16ENSG0000012991117
SP5 / Q6BEB4 / Sp5 transcription factorENSG0000020433517
KLF9 / Q13886 / Kruppel like factor 9ENSG0000011913817
SP9 / P0CG40 / Sp9 transcription factorENSG0000021723616
SP6 / Q3SY56 / Sp6 transcription factorENSG0000018912015


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0009267 cellular response to starvation ISS
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0045672 positive regulation of osteoclast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:1901653 cellular response to peptide IEA
 cellular_componentGO:0005634 nucleus TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding ISS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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