ENSG00000112079


Homo sapiens

Features
Gene ID: ENSG00000112079
  
Biological name :STK38
  
Synonyms : Q15208 / serine/threonine kinase 38 / STK38
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.31
Gene start: 36493892
Gene end: 36547470
  
Corresponding Affymetrix probe sets: 1553117_a_at (Human Genome U133 Plus 2.0 Array)   1557145_at (Human Genome U133 Plus 2.0 Array)   202951_at (Human Genome U133 Plus 2.0 Array)   216451_at (Human Genome U133 Plus 2.0 Array)   216727_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000229812
NCBI entrez gene - 11329     See in Manteia.
OMIM - 606964
RefSeq - XM_017010226
RefSeq - NM_001305102
RefSeq - NM_007271
RefSeq - XM_006714988
RefSeq - XM_006714989
RefSeq Peptide - NP_001292031
RefSeq Peptide - NP_009202
swissprot - Q15208
swissprot - A0A024RD18
Ensembl - ENSG00000112079
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk38aENSDARG00000019973Danio rerio
 stk38bENSDARG00000018516Danio rerio
 STK38ENSGALG00000000523Gallus gallus
 Stk38ENSMUSG00000024006Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y2H1 / STK38L / serine/threonine kinase 38 likeENSG0000021145587
LATS2 / Q9NRM7 / large tumor suppressor kinase 2ENSG0000015045744
LATS1 / O95835 / large tumor suppressor kinase 1ENSG0000013102342
Q5VT25 / CDC42BPA / CDC42 binding protein kinase alphaENSG0000014377637
Q9Y5S2 / CDC42BPB / CDC42 binding protein kinase betaENSG0000019875236
Q6DT37 / CDC42BPG / CDC42 binding protein kinase gammaENSG0000017121936
ROCK1 / Q13464 / Rho associated coiled-coil containing protein kinase 1ENSG0000006790034
ROCK2 / O75116 / Rho associated coiled-coil containing protein kinase 2ENSG0000013431833
DMPK / Q09013 / DM1 protein kinaseENSG0000010493632
CIT / O14578 / citron rho-interacting serine/threonine kinaseENSG0000012296630


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IDA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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